Results 101 to 110 of about 595,200 (266)

Association of Myocardial Deformation With Mortality Independent of Myocardial Ischemia and Left Ventricular Hypertrophy

open access: yes, 2009
Objectives: The aim of this study was to investigate the relative contributions of left ventricular hypertrophy (LVH) and myocardial ischemia to the association between abnormal myocardial deformation during dobutamine stress echocardiography (DSE) and ...
Leano, R   +4 more
core   +1 more source

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu   +7 more
wiley   +1 more source

Is it silent myocardial ischemia?! - case report [PDF]

open access: yes, 2014
Department of Internal Medicine, University of Medicine and Pharmacy “Gr.T. Popa” Iasi, RomaniaIntroduction: Silent myocardial ischemia is defined as objective documentation of myocardial ischemia in the absence of angina or anginal equivalents. Silent
Vranescu, Andreea, Bursuc, Elena
core   +1 more source

Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling [PDF]

open access: yes, 2001
The "metabolic cocktail" comprising glucose-insulin-potassium administrated at reperfusion reduces infarct size in the in vivo rat heart. We propose that insulin is the major component mediating this protection and acts via Akt prosurvival signaling ...
Sack, M.N.   +3 more
core  

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza   +12 more
wiley   +1 more source

The Diagnostic Value of Tc-99m MIBI Gated Myocardial Perfusion SPECT in Detection of Silent Myocardial Ischemia in Asymptomatic Patients with Type 2 Diabetes Mellitus

open access: yesEurasian Journal of Medicine, 2019
Objective: In this study, we aimed to evaluate the diagnostic value of Technetium-99m methoxyisobutylisonitrile (Tc-99m MIBI) gated myocardial perfusion SPECT (MPS) in the detection of coronary artery disease (CAD) and silent myocardial ischemia (SMI) in
Coskun Ak, Ali Sahin, Ilyas Capoglu
doaj  

Hypertension and myocardial ischemia

open access: yes, 2009
There is an impressive evidence base for the presence of myocardial ischemia in patients who have hypertension. This relationship ranges from the obvious association with obstructive coronary artery disease to more subtle mechanisms related to ...
Dunn, Francis G.   +5 more
core   +1 more source

The functional significance of vasomotor arteries dysfunction in the clinical assessment of myocardial ischemia in case of carbohydrate metabolism disorder

open access: yesКардиоСоматика, 2014
We investigated the relationship between the severity of silent myocardial ischemia and the functional state of arteries endothelium. We studied the significance of violations of vasomotor function with the loss of the ability to flow-dependent ...
I. P Tatarchenko   +3 more
doaj  

Atomically precise metal cluster enzymes for pathological tissue regeneration

open access: yesBMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong   +11 more
wiley   +1 more source

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