Results 81 to 90 of about 631,189 (236)

The clinical and functional evaluation of cardiac electrical instability in patients with silent myocardial ischemia

open access: yesТерапевтический архив, 2010
Aim. To study markers of myocardial electrical instability in patients with coronary heart disease (CHD) during silent myocardial ischemic episodes. Subjects and methods. Eighty-two patients with stable CHD (mean age 62.6 ± 5.4 years) were examined.
Ivan Porfir'evich Tatarchenko   +7 more
doaj  

Squatting stress echocardiography potential in coronary heart disease diagnostics

open access: yesРоссийский кардиологический журнал, 2013
While stress echocardiography (EchoCG) is widely used in clinical practice for diagnosing silent myocardial ischemia, the search for new stress tests remains an important task in the diagnostics of coronary heart disease (CHD). Aim.
V. A. Kuznetsov   +5 more
doaj   +1 more source

An Infusible Decellularized Extracellular Matrix Material Binds to Vasculature in Infarcted Myocardium and Induces Pro‐Reparative Gene Expression Following Acute Myocardial Infarction Through Inherent Avidity and Bioactive Signaling

open access: yesAdvanced Science, EarlyView.
To better characterize an infusible extracellular matrix (iECM) material, we applied size‐based fractionation to separate out components into two major fractions. We characterized these fractions to understand how material properties such as composition, morphology, and biochemical properties affect bioactive effects in the context of acute myocardial ...
Michael B. Nguyen   +13 more
wiley   +1 more source

Ischemic Postconditioning Protects Aged Myocardium Against Ischemia/Reperfusion Injury by Regulating Mitochondrial Dynamics via piR‐4913

open access: yesAdvanced Science, EarlyView.
A tiny RNA tips the scales of cardiac injury in aging. piR‐4913 recruits OGT to Drp1 and drives its O‐GlcNAcylation at Thr604, promoting excessive mitochondrial fission that aggravates ischemia‐reperfusion injury. Ischemic postconditioning silences this pathway to restore mitochondrial balance and protect the aged myocardium, revealing piR‐4913 as a ...
Xiangyu Zhao   +11 more
wiley   +1 more source

Metabolic syndrome and coronary heart disease

open access: yesТерапевтический архив, 2014
The literature review presents current views on micro- and macrovascular disorders in metabolic syndrome characterized by silent myocardial ischemia detectable only during exercise and myocardial radionuclide scintigraphy.
S V Gurgenian   +2 more
doaj  

Angina de peito. Isquemia silenciosa.

open access: yesActa Médica Portuguesa, 1997
One of the most difficult problems related to coronary artery disease is the detection and eventual treatment of silent myocardial ischemia (SMI). After defining the concept of SMI and total ischemia burden, the author approaches the pathophysiology of ...
J L Tuna
doaj   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

open access: yesAGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

New Aspects for the Treatment of Cardiac Diseases Based on the Diversity of Functional Controls on Cardiac Muscles: The Regulatory Mechanisms of Cardiac Innervation and Their Critical Roles in Cardiac Performance

open access: yesJournal of Pharmacological Sciences, 2009
The heart is abundantly innervated, and the nervous system precisely controls the function of this organ. The density of cardiac innervation is altered in diseased hearts, which can lead to unbalanced neural activation and lethal arrhythmia. For example,
Masaki Ieda, Keiichi Fukuda
doaj   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

open access: yesAdvanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò   +7 more
wiley   +1 more source

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