Results 171 to 180 of about 595,200 (266)

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Significance of Microalbuminuria in Predicting Silent Myocardial Ischemia in Patients with Type 2 Diabetes Using Myocardial Perfusion Imaging [PDF]

Mol Imaging Radionucl Ther, 2019
Emami T, Naeimei Z, Salehifard A, Azizmohammadi Z, Iranpour D, Kalantarhormozi M, Kalantarhormozi M, Jafari E, Gholamrezanezhad A, Assadi M.   +9 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Current strategies to enhance the target efficiency of advanced multifunctional ultrasound contrast agents in ischemic diseases

Interdisciplinary Medicine, EarlyView.
The graphical abstract outlines a novel multifunctional ultrasound contrast agent for the diagnosis and treatment of ischemic diseases, along with innovative strategies to enhance its targeting efficiency. Abstract Ischemic diseases, such as myocardial infarction, stroke, and peripheral ischemia, are leading causes of death and disability worldwide ...
Yangyang Zhou, Jing Lin, Yu Chen, Jiaqi Zhao   +3 more
wiley   +1 more source

Radial Pulse Spectrum Analysis as Risk Markers to Improve the Risk Stratification of Silent Myocardial Ischemia in Type 2 Diabetic Patients. [PDF]

IEEE J Transl Eng Health Med, 2018
Chang CW, Liao KM, Chen YC, Wang SH, Jan MY, Wang GC.   +5 more
europepmc   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, EarlyView.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

Periodontitis and its association with left ventricular geometry and function: A cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background This study investigated the cross‐sectional association between periodontal status and left ventricular (LV) geometry and function, an early and prognostically relevant marker of cardiovascular disease. Methods Data were drawn from two population‐based cohorts in the Study of Health in Pomerania (SHIP): SHIP‐START‐2 (N = 2333) and ...
Maja Trost, Till Ittermann, Birte Holtfreter, Christiane Pink, Marcus Dörr, Henry Völzke, Matthias Nauck, Marcello Ricardo Paulista Markus, Thomas Kocher   +8 more
wiley   +1 more source

Non‐linear association between tooth loss and cardiovascular diseases among middle‐aged adults

Journal of Periodontology, EarlyView.
Abstract Background Although positive associations between fewer remaining teeth and an increased risk of various systemic diseases have been reported, the precise dose‐response relationship has not been fully clarified. This study aimed to evaluate the non‐linearity of the dose‐response association between the number of lost teeth and the risk of ...
Taro Kusama, Yudai Tamada, Takashi Miyano, Megumi Maeda, Futoshi Oda, Ken Osaka, Haruhisa Fukuda, Kenji Takeuchi   +7 more
wiley   +1 more source

Triglyceride‐Glucose Index‐Based Nomogram for Predicting Short‐Term Mortality in Sepsis Patients

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The triglyceride‐glucose (TyG) index, a marker of insulin resistance, is associated with outcomes in critical illness; however, its predictive role for 28‐day mortality in Asian patients with sepsis has not been established. To address this, the current investigation was designed to evaluate its prognostic significance and to construct a risk ...
Jing Zhang, Yu‐Jing Jiang, Ya‐Ting Lv, Tong‐Qin Li, Li Ma   +4 more
wiley   +1 more source