Results 171 to 180 of about 631,189 (236)

Periodontitis and its association with left ventricular geometry and function: A cross‐sectional study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This study investigated the cross‐sectional association between periodontal status and left ventricular (LV) geometry and function, an early and prognostically relevant marker of cardiovascular disease. Methods Data were drawn from two population‐based cohorts in the Study of Health in Pomerania (SHIP): SHIP‐START‐2 (N = 2333) and ...
Maja Trost   +8 more
wiley   +1 more source

Non‐linear association between tooth loss and cardiovascular diseases among middle‐aged adults

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Although positive associations between fewer remaining teeth and an increased risk of various systemic diseases have been reported, the precise dose‐response relationship has not been fully clarified. This study aimed to evaluate the non‐linearity of the dose‐response association between the number of lost teeth and the risk of ...
Taro Kusama   +7 more
wiley   +1 more source

Causal inference in oral health research: Beyond statistical significance toward a causal framework

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Oral health research has adopted sophisticated statistical methods, yet studies routinely present adjusted associations as causal effects. The problem is not statistical competence but the absence of explicit causal reasoning. This commentary proposes a principled framework for causal reasoning in oral health research.
Jack M. Wolf   +2 more
wiley   +1 more source

Anti‐hypercholesterolemic effects of barley and its role in the management of metabolic disorders: A comprehensive review

open access: yesJSFA reports, EarlyView.
Abstract The dietary and lifestyle practices have predominantly compromised human health, which are influenced by modernization and industrialization. Hypercholesterolemia, caused by the consumption of fatty and fried foods and a sedentary lifestyle, is a major modifiable risk factor for cardiovascular disease and commonly coexists with obesity ...
Muhammad Usman Khalid   +8 more
wiley   +1 more source

Gastrointestinal Cancer Surgery in Patients on Maintenance Hemodialysis: A Prisma Guided Systematic Review and Propensity Score Matched Cohort Analysis

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background Patients receiving maintenance hemodialysis (HD) have limited physiologic reserve and high competing cardiometabolic risk, yet surgery remains central to cure for many gastrointestinal (GI) malignancies. Evidence describing oncologic surgery in this population is fragmented across cancer sites and data sources.
Ali Abdelhady   +7 more
wiley   +1 more source

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song   +7 more
wiley   +1 more source

Hemodynamic Significance of APEXCT Coronary Angiography Combined With Dynamic CT Myocardial Perfusion Imaging in Assessing Restenosis After Coronary Stenting

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to evaluate the hemodynamic significance of in‐stent restenosis (ISR) by using a combined anatomical‐functional approach with photon‐counting CT coronary angiography (APEX‐CT CTA) and dynamic CT myocardial perfusion imaging (CT‐MPI). We prospectively enrolled 239 symptomatic patients at least 9 months after PCI.
Liang‐Shi Wang   +6 more
wiley   +1 more source

Kaempferol Attenuates Myocardial Ischemia–Reperfusion Injury by Suppressing Ferroptosis via the KEAP1–Nrf2–GPX4 Axis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao   +6 more
wiley   +1 more source

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