Results 71 to 80 of about 1,477,101 (250)

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Lithium‐related adverse drug reactions in children: A case–control study comparing lithium to second‐generation antipsychotics in VigiBase

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to improve the understanding of lithium's safety profile by analysing the frequency and distribution of reported adverse drug reactions (ADRs) compared to second‐generation antipsychotics (SGAs). Methods Individual case safety reports from VigiBase (1968–October 2023) involving individuals older than 2 years, with lithium or SGAs ...
Lisa T. Ringeling   +8 more
wiley   +1 more source

A Case of Silent Sinus Syndrome Caused by a Dacryocystorhinostomy Presenting as Myasthenia Gravis

open access: yes, 2014
Silent Sinus Syndrome (SSS) is a rare entity defined as spontaneous, progressive enophthalmos and hypoglobus from maxillary sinus hypoplasia due to chronic maxillary sinus obstruction1.
Peter G. Coombs; Jamie Mitchell; Gary Lelli; Marc Dinkin
core  

Exploring the early observations of parents supporting their children with school attendance problems (SAPs): A co‐produced study

open access: yesBritish Educational Research Journal, EarlyView.
Abstract School Attendance Problems (SAPs) represent a significant challenge requiring early identification and intervention. Current service provision often does not recognise early indicators that parents observe, creating gaps between when initial concerns are raised and formal support is provided.
Tereza Aidonopoulou‐Read   +4 more
wiley   +1 more source

Chiari I Malformation: Review and Update of Current Treatment Options

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo   +11 more
wiley   +1 more source

Stage II Chronic Maxillary Atelectasis Associated with Subclinical Visual Field Defect

open access: yesInternational Archives of Otorhinolaryngology, 2013
Introduction Chronic maxillary atelectasis (CMA) is characterized by a persistent decrease in the maxillary sinus volume due to inward bowing of its walls. According to its severity, it may be classified into three clinical-radiological stages.
João Mangussi-Gomes   +4 more
doaj   +1 more source

Acquired unilateral pseudoptosis: a presentation of silent sinus syndrome.

open access: yes, 2006
BACKGROUND: Acquired unilateral ptosis usually results from either levator palpebrae disinsertion, eyelid disorder, myasthenia gravis, mitochondrial myopathy, Horner's syndrome, or third nerve palsy.
Borruat, F.X., Kaeser, P.F.
core   +1 more source

Developmental Morphometry of the Paranasal Sinuses in Subjects Aged 1–25 Years: A Computed Tomography Study

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The present study aimed to evaluate the developmental morphometry of the paranasal sinuses using computed tomography (CT) in subjects aged 1–25 years and to characterize age‐related changes in sinus dimensions, volume, and surface area throughout childhood, adolescence, and young adulthood.
Ceyda Şevval Çetin   +4 more
wiley   +1 more source

Hemodynamic loading regulates formation and patterning of atrial pectinate muscles in the chick embryo

open access: yesDevelopmental Dynamics, EarlyView.
Development and differentiation of the atrial myocardium. Hemodynamic loading triggers shear stress response, which is essential for pectinate muscle formation; mechanical stretching is important for the expression of chamber myocardium markers and proper maturation of the atrial contractile and conductive properties.
C. Neradilova   +7 more
wiley   +1 more source

CARDIOGENIC INSULTS

open access: yesНеврология, нейропсихиатрия, психосоматика, 2009
Based on the current data available in the literature and the results of his studies, the author characterizes the implication of cardiac diseases in the pathogenesis of cardioembolic and hemodynamic insults.
A. V. Fonyakin, L. A. Geraskina
doaj   +1 more source

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