Results 91 to 100 of about 41,841 (256)

Integrated multi-omics analyses reveal the pro-inflammatory and pro-fibrotic pulmonary macrophage subcluster in silicosis

open access: yesEcotoxicology and Environmental Safety
Background: Silicosis is a lethal occupational disease caused by long-term exposure to respirable silica dust. Pulmonary macrophages play a crucial role in mediating the initiation of silicosis.
Hanyujie Kang   +4 more
doaj   +1 more source

The single nucleotide polymorphism rs1814521 in long non-coding RNA ADGRG3 associates with the susceptibility to silicosis: a multi-stage study

open access: yesEnvironmental Health and Preventive Medicine, 2022
Background: This study aimed to evaluate the correlation between long non-coding RNA (lncRNA)-related single nucleotide polymorphisms (SNPs) and susceptibility to silicosis.
Wei Wang   +10 more
doaj   +1 more source

Assessment of Occupational Diseases among Artisans and Factory Workers in Ifo, Nigeria [PDF]

open access: yes, 2013
The ever increasing incidences of occupational diseases among workers have continually drawn the attention of researchers towards ameliorating the situation.
Dahunsi, S. O.   +2 more
core  

MicroRNA‐205‐5p targets E2F1 to promote autophagy and inhibit pulmonary fibrosis in silicosis through impairing SKP2‐mediated Beclin1 ubiquitination

open access: yesJournal of Cellular and Molecular Medicine, 2021
Silicosis is an occupational disease characterized by extensive pulmonary fibrosis, and the underlying pathological process remains uncertain. Herein, we explored the molecular mechanism by which microRNA‐205‐5p (miR‐205‐5p) affects the autophagy of ...
Qingzeng Qian   +6 more
semanticscholar   +1 more source

Endothelial‐Derived CCL7 Promotes Macrophage Polarization and Aggravates Septic Acute Lung Injury via CCR1‐Mediated STAT1 Succinylation

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
During sepsis, pulmonary vascular endothelial cells secrete chemokine CCL7, which plays a pivotal role in facilitating the infiltration of C‐C motif chemokine receptor 1‐positive (CCR1+) macrophages into lung tissue. Activation of the CCL7–CCR1 axis enhances the succinylation of STAT1 mediated by KAT2A, thereby driving metabolic reprogramming and ...
Xue Li   +5 more
wiley   +1 more source

No. 24: Spaces of Vulnerability: Migration and HIV/AIDS in South Africa [PDF]

open access: yes, 2002
Seventy per cent of the 36 million people infected worldwide with HIV live in Sub-Saharan Africa and within this region the countries of Southern Africa are the worst affected.
Crush, Jonathan   +3 more
core   +1 more source

Silicosis: controversy in detection [PDF]

open access: yesMedicina y Seguridad del Trabajo, 2014
Artículo especial [EN] In many countries, the work of mining, quarrying, construction of tunnels and galleries, abrasive jet cleaning and smelting continue to present significant risks of silica exposure and silicosis epidemics still occur, even in developed countries.
openaire   +6 more sources

The Therapeutic Potential of Andrographolide and Its Derivatives in Inflammatory Diseases

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
ABSTRACT Andrographolide, a diterpenoid component found in traditional Chinese medicine Andrographis paniculata, is known as a natural antibiotic and can be used to treat inflammatory lesions of various systemic diseases. In recent years, andrographolide derivatives have been continuously synthesized and have shown good anti‐inflammatory ...
Xiaoqin Shan   +7 more
wiley   +1 more source

Tuberculosis and Silicosis: an insightful perspective

open access: yesEgyptian Journal of Chest Disease and Tuberculosis
Tuberculosis (TB) is the most ubiquitous disease related to Silicosis in medium and low-income nations. The government of India has set a target to eliminate TB by 2025, while the International Labor Organization and the WHO aim to eradicate Silicosis ...
Shally Pandit   +4 more
doaj   +1 more source

Novel functional eQTL-SNPs associated with susceptibility to occupational pulmonary fibrosis: A multi-stage study

open access: yesEcotoxicology and Environmental Safety
Aim: Identifying the common functional single-nucleotide polymorphisms (SNPs) that can both affect the susceptibility to idiopathic pulmonary fibrosis (IPF) and silicosis.
Rui Zhao   +9 more
doaj   +1 more source

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