Results 101 to 110 of about 41,841 (256)

The Case for Autoantibody Screening in Stone Benchtop Workers

Respirology Case Reports, Volume 13, Issue 10, October 2025.
We present the case of a 40‐year‐old stone benchtop worker who was diagnosed with complicated silicosis on screening, with early ANA positivity preceding the development of progressive multisystem autoimmune disease and respiratory decline. This case underscores the potential for silica exposure to trigger severe autoimmune disease in addition to ...
Tiffany Lin, Jun Keng Khoo, Ryan Hoy
wiley   +1 more source

Analysis of PM2.5 Morphology, Composition and Health Risk in a Multi‐Chair Dental Clinic

Environmental Toxicology, Volume 40, Issue 10, Page 1207-1219, October 2025.
ABSTRACT Particulate matter with aerodynamic diameter ≤ 2.5 μm (PM2.5) at high concentrations in dental clinics poses significant health risks to healthcare professionals. However, the morphology and chemical composition of PM2.5 in specific environments are not yet fully elucidated.
Fengqin Tang, Shengcai Qi, Xiaoshan Tang, Xueyun Wen, Yiming Zhang, Guotao Peng, Jieying Huang, Guangwei Shang, Xu Zhang, Fubo Chen, Yuanzhi Xu, Jing Cai   +11 more
wiley   +1 more source

Genome-wide mRNA profiling identifies the NRF2-regulated lymphocyte oxidative stress status in patients with silicosis

Journal of Occupational Medicine and Toxicology, 2021
Background The immunomodulatory abnormalities of silicosis are related to the lymphocyte oxidative stress state. The potential effect of antioxidant therapy on silicosis may depend on the variation in nuclear factor erythroid 2-related factor 2 (NRF2 ...
Yingzheng Zhao, Guangcui Xu, Haibin Li, Meiyu Chang, Cheng Xiong, Yingjun Tao, Yi Guan, Yuchun Li, Sanqiao Yao   +8 more
doaj   +1 more source

Smoking Promotes AT2 Cell Senescence and Exacerbates Pulmonary Fibrosis by Downregulating POT1 via Integratively Inducing CpG Methylation and MECP2‐Mediated FOXP2 Transcriptional Binding Inhibition

Aging Cell, Volume 24, Issue 10, October 2025.
Smoking is one of the major causes of pulmonary fibrosis (PF), and treatment options for PF are limited. We show that POT1 is decreased in PF patients and mice, especially in smoke exposure, and investigate its contributions to PF progression from protecting AT2 cell senescence to fibrosis. AAV9‐mediated restoration of POT1 prevents PF.
Mengkun Shi, Wei Wang, Posum Wan, Jialun Shi, Huixia Cui, Zhonghan Sun, Xiaofeng Chen, Jingyu Chen, Jiucun Wang, Xiangguang Shi   +9 more
wiley   +1 more source

Corporate Social Responsibility and the Mining Sector in Southern Africa: A Focus on Mining in Malawi, South Africa and Zambia [PDF]

, 2008
The research conducted by the Bench Marks Foundation on mining in Southern provides SADC governments, mining companies and local mining community stakeholders with information and guidance on issues to consider in the process of empowerment and ...

core  

Immunity Switches and Macrophage Manipulations: Trauma, Ovulation, and Depression as Latent Tuberculosis Reactivation Risks

American Journal of Human Biology, Volume 37, Issue 9, September 2025.
ABSTRACT Inflammation is the immune system's natural response to initial tuberculosis infection. Tuberculosis bacteria have gained adaptations to manipulate the inflammatory process, sometimes settling into latency and containment in granulomas, ensuring their survival.
Stacie Burke
wiley   +1 more source

CC-chemokine ligand 18, CXC motif chemokine 13 and osteopontin as biomarkers of silicosis and asbestosis: a prospective observational study

Scientific Reports
Background Silicosis and asbestosis, distinct forms of pneumoconiosis, manifest progressive interstitial fibrosis due to exposure to silica dust or asbestos fibers. This study aimed to identify potential biomarkers for diagnosing silicosis and asbestosis,
Na Wu, Changjiang Xue, Shiwen Yu, Yuanying Wang, Di Sun, Qiao Ye   +5 more
doaj   +1 more source

Clinical usefulness of serum angiotensin converting enzyme in silicosis

Pulmonology
Introduction Silicosis is an irreversible and incurable disease. Preventive measures to eliminate exposure are the only effective way to reduce morbidity and mortality.
J. Blanco-Pérez, Á. Salgado-Barreira, S. Blanco-Dorado, M.E. González Bello, A.C. Caldera Díaz, A. Pérez-Gonzalez, A. Pallarés Sanmartín, A. Fernández Villar, F.J. Gonzalez-Barcala   +8 more
doaj   +1 more source

Disruption of Spike Priming in Virus Entry: Tetrandrine as a Pan‐Coronavirus Inhibitor

MedComm, Volume 6, Issue 9, September 2025.
Tetrandrine inhibits the infection of HCoV‐OC43, HCoV‐229E, SARS‐CoV‐2, and its major variants by blocking virus entry. Specifically, tetrandrine breaks the interaction between TMPRSS2 and Spike, therefore suppress its priming and the following membrane fusion, and induces Spike to degradation.
Kun Wang, Huiqiang Wang, Shuo Wu, Ge Yang, Haiyan Yan, Lijun Qiao, Xingqiong Li, Mengyuan Wu, Jiandong Jiang, Yuhuan Li   +9 more
wiley   +1 more source

Clinical and radiological features of pulmonary disease due to culture-positive M. tuberculosis or nontuberculous mycobacteria in South African gold miners. [PDF]

, 2005
Pulmonary mycobacterial disease may be due to Mycobacterium tuberculosis or nontuberculous mycobacteria ...
Glyn Thomas, R, Glynn, JR, Godfrey-Faussett, P, Murray, J, Shearer, S, Sonnenberg, P   +5 more
core   +2 more sources