Results 111 to 120 of about 50,422 (305)

Clinical usefulness of serum angiotensin converting enzyme in silicosis

open access: yesPulmonology
Introduction Silicosis is an irreversible and incurable disease. Preventive measures to eliminate exposure are the only effective way to reduce morbidity and mortality.
J. Blanco-Pérez   +8 more
doaj   +1 more source

Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, Volume 12, Issue 27, July 17, 2025.
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui   +17 more
wiley   +1 more source

Diosgenin ameliorates silica‐induced tuberculosis in rats

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 7, Page 1186-1195, July 2025.
Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu   +5 more
wiley   +1 more source

Clinical and radiological features of pulmonary disease due to culture-positive M. tuberculosis or nontuberculous mycobacteria in South African gold miners. [PDF]

open access: yes, 2005
Pulmonary mycobacterial disease may be due to Mycobacterium tuberculosis or nontuberculous mycobacteria ...
Glyn Thomas, R   +5 more
core   +2 more sources

Intratracheal Administration of Nanoplastics With Varying Surface Hydrophobicity Results in Coarsely Vacuolated Alveolar Macrophages, Transient Respiratory Inflammation, and Mild Collagen Deposition

open access: yesNano Select, Volume 6, Issue 7, July 2025.
Nanoplastic hydrophobicity drives adverse effects in the lung. Single intratracheal administration of poly(vinyl acetate‐co‐alcohol) nanoplastics with varying surface hydrophobicity shows that the more hydrophobic nanoplastics increase prevalence of coarsely vacuolated alveolar macrophages, induce transient respiratory inflammation and mild collagen ...
Anna Babin Morgan   +9 more
wiley   +1 more source

Asbestosis Requiring Lung Transplantation in a Retired Hairdresser: An Occupational Exposure to Comb Through

open access: yesRespirology Case Reports, Volume 13, Issue 7, July 2025.
Asbestos is a group of naturally occurring, fibrous silicate minerals, which if inhaled can lead to the development of fibrotic interstitial lung disease as well as other pulmonary pathology. Several professions are historically known to be associated with asbestos exposure; however, hairdressers are not considered to be one of them.
Ruojin Bu   +9 more
wiley   +1 more source

ILC2 Diversity, Location, and Function in Pulmonary Disease

open access: yesImmunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma   +2 more
wiley   +1 more source

Development of a compact excavator mounted dust suppression system [PDF]

open access: yes, 2013
This paper reports on the investigation of an excavator mounted dust suppression system for demolition and construction activities. Ever increasing pressure is placed on contractors to improve their environmental performance, especially dust emissions ...
Ahn   +32 more
core   +1 more source

Latent tuberculosis infection and infection-associated risk factors for miner workers with silicosis in eastern China

open access: yesBMC Pulmonary Medicine
Objectives Silicosis people are at high risk of developing pulmonary tuberculosis. Whether silica exposure increases the likelihood of latent tuberculosis infection (LTBI) was not well understood, and potential factors involved in LTBI risk among ...
Xinsong Hu   +9 more
doaj   +1 more source

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