Results 51 to 60 of about 4,418,602 (386)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

State of the art in human risk assessment of silver compounds in consumer products: a conference report on silver and nanosilver held at the BfR in 2012

Archives of Toxicology, 2013
In light of the broad spectrum of products containing nanosilver, the harmfulness of nanosilver to human health and the environment was intensively discussed at a conference held in February 2012 at the BfR.
Bernd Schäfer, J. V. Brocke, A. Epp, M. Götz, Frank Herzberg, C. Kneuer, Y. Sommer, J. Tentschert, M. Noll, Isabel Günther, U. Banasiak, G. Böl, A. Lampen, A. Luch, A. Hensel   +14 more
semanticscholar   +1 more source

Silver Staining of Proteins in 2DE Gels [PDF]

, 2009
Silver staining detects proteins after electrophoretic separation on polyacrylamide gels. Its main positive features are its excellent sensitivity (in the low nanogram range) and the use of very simple and cheap equipment and chemicals.
Chevallet, Mireille, Lelong, Cécile, Luche, Sylvie, Rabilloud, Thierry   +3 more
core   +5 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Investigation of Silver Nitrate on Cytotoxicity and Apoptosis in MCF7 Human Breast Carcinoma Cells

Asian Pacific Journal of Cancer Biology, 2020
Background: Metal compounds have been studied in vitro for many years and these compounds’s effects are shown on tumors. Anticancer potential of silver and silver metal compounds is investigated in these days.
Ayse Kaplan, Hatice Mehtap Kutlu
doaj   +1 more source

Non-thermal plasma technology for the development of antimicrobial surfaces: a review [PDF]

, 2016
Antimicrobial coatings are in high demand in many fields including the biomaterials and healthcare sectors. Within recent progress in nanoscience and engineering at the nanoscale, preparation of nanocomposite films containing metal nanoparticles ( such ...
Cvelbar, U, De Geyter, Nathalie, Deng, XL, Leys, Christophe, Morent, Rino, Nikiforov, Anton, Xiong, Q   +6 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Novel Azoles as Antiparasitic Remedies against Brain-Eating Amoebae

Antibiotics, 2020
Balamuthia mandrillaris and Naegleria fowleri are opportunistic protozoan pathogens capable of producing infection of the central nervous system with more than 95% mortality rate.
Ayaz Anwar, Mohammad Ridwane Mungroo, Simal Khan, Itrat Fatima, Rafaila Rafique, Kanwal, Khalid Mohammed Khan, Ruqaiyyah Siddiqui, Naveed Ahmed Khan   +8 more
doaj   +1 more source

Monitoring Corrosion Products on Metal Artefacts by Linear Sweep Voltammetry (LSV) [PDF]

, 2012
Metallic surfaces are highly sensitive to their surroundings, and prone to react with airborne pollutants to form complex layers. Electrochemical techniques have the possibility of simultaneously identifying different electroactive compounds [1].
Capelo, Sofia, Cavalheiro, J., Fonseca, I.T.E., Homem, P.   +3 more
core  

Silicon electrodeposition in molten fluorides [PDF]

, 2011
Silicon nucleation process was investigated in molten NaF-KF (40-60 mol%) on silver electrodes in the 820-950°C temperature range in order to optimize silicon coating operating conditions.
Bieber, Anne-Laure, Cassayre, Laurent, Chamelot, Pierre, Gibilaro, Mathieu, Massot, Laurent, Taxil, Pierre   +5 more
core   +1 more source