Results 211 to 220 of about 218,831 (262)

Simian immunodeficiency virus vectors: Replication and pseudotyping

Journal of Medical Primatology, 1992
We studied a single round of replication of Simian immunodeficiency virus (SIV) through the use of a replication defective vector that expresses the hygromycin resistance gene. It was possible to pseudotype SIV particles by complementation with the env gene from a murine amphotropic retrovirus.
T A, Rizvi, A T, Panganiban
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Pathogenic mechanisms in simian immunodeficiency virus infection

Current Opinion in HIV and AIDS, 2008
Recent work in pathogenic simian immunodeficiency (SIV) infection of Asian macaques and in natural, nonpathogenic SIV infections of African nonhuman primate species has demonstrated that persistent activation has profound effects on CD4+ memory T-cell proliferation, differentiation and survival.
Zvi, Grossman, Louis J, Picker
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Interstitial pneumonia in simian immunodeficiency virus infection

The Journal of Pathology, 1992
AbstractInterstitial pneumonia unrelated to Pneumocystis carinii or other infections was observed histopathologically in 5 of 25 rhesus monkeys infected with simian immunodeficiency virus (SIV). The predominant lesion was lymphocytic infiltration of interalveolar septa and hyperplasia of peribronchial and perivascular lymphoid tissue ...
A, Baskerville, A D, Ramsay, B J, Addis, M J, Dennis, R W, Cook, M P, Cranage, P J, Greenaway   +6 more
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Vectors derived from simian immunodeficiency virus (SIV)

Biochimie, 2002
In contrast to other retroviruses, lentiviruses have the unique property of infecting non-proliferating cells. Thus vectors derived from lentiviruses are promising tools for in vivo gene delivery applications. Vectors derived from human primate and non-primate lentiviruses have recently been described and, unlike retroviral vectors derived from murine ...
Didier, Nègre, François-Loïc, Cosset
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Histopathological changes in simian immunodeficiency virus infection

The Journal of Pathology, 1990
AbstractThe histological lesions were studied in seven rhesus and three cynomolgus monkeys infected with simian immunodeficiency virus for periods ranging from nine weeks to 18 months. Lymphoreticular changes included hyperplasia, follicular involution and depletion, and one animal had amyloidosis of the spleen.
A, Baskerville, A, Ramsay, M P, Cranage, N, Cook, R W, Cook, M J, Dennis, P J, Greenaway, P A, Kitchin, E J, Stott   +8 more
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Simian Immunodeficiency Virus in People

New England Journal of Medicine, 1994
The simian immunodeficiency viruses (SIVs) were initially identified on the basis of antibody cross-reactivity with human immunodeficiency virus type 1 (HIV-1)1. Serum samples from macaque monkeys from Asia with AIDS-like diseases were found to have antibodies that reacted with HIV-1 antigens.
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Simian immunodeficiency virus reverse transcriptase

European Journal of Biochemistry, 1990
Native reverse transcriptase from simian immunodeficiency virus was purified from virus with good recovery to near homogeneity. The optimum reaction conditions of the enzyme were determined with respect to divalent cations, pH and ionic strength. The enzyme was shown to possess both RNA‐dependent and DNA‐dependent DNA synthesis activity.
G, Kraus, E, Behr, M, Baier, H, König, R, Kurth   +4 more
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Simian immunodeficiency virus mac251 infection of astrocytes

Journal of Neurovirology, 2000
Human immunodeficiency virus type 1 (HIV-1) infection of astrocytes has been demonstrated in the brains of patients with AIDS dementia complex (ADC) and may play an important role in neuropathological pathways of HIV-related encephalopathy. SIVmac-infected monkeys develop an acquired immunodeficiency syndrome (AIDS) with CNS involvement which is quite ...
G, Guillemin, J, Croitoru, R L, Le Grand, M, Franck-Duchenne, D, Dormont, F D, Boussin   +5 more
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Simian Immunodeficiency Virus Infections

1993
African species of nonhuman primates harboring persistent simian immunodeficiency virus (SIV) infections do not develop clinical illness or gross lesions. These species include: African green monkeys infected with SIVAGM, sooty mangabey monkeys infected with SIVSMM(δ), Sykes’ monkeys infected with SIVSYK; mandrills infected with SIVMND, and chimpanzees
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Mucosal Transmission of Simian Immunodeficiency Virus

1994
Although human immunodeficiency virus (HIV) is transmitted primarily by heterosexual contact very little is understood about the biology of heterosexual transmission of HIV. Epidemiological studies indicate that HIV is not efficiently transmitted by sexual contact. In fact many other sexually transmitted diseases (STDs) are more efficiently transmitted.
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