Results 101 to 110 of about 1,779,341 (295)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

On the Markovian Similarity [PDF]

open access: yes, 2018
Two finite Markov generators $L$ and $\widetilde L$ are said to be intertwined if there exists a Markov kernel $\Lambda$ such that $L\Lambda=\Lambda\widetilde L$. The goal of this paper is to investigate the equivalence relation between finite Markov generators obtained by imposing mutual intertwinings through invertible Markov kernels, in ...
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Pengelompokan UMKM Batik Madura Menggunakan Metode K-Means dan Sillhoutte Coefficient

open access: yesTeknika
UMKM merupakan salah satu sektor pendukung perekonomian di Indonesia. UMKM Batik Madura memberikan kontribusi yang cukup tinggi terhadap penyerapan tanaga kerja dan peningkatan ekonomi masyarakat daerah. Hal ini terbukti pada penyerapan tenaga kerja UMKM
Yeni Kustiyahningsih   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Enhancing timbre model using MFCC and its time derivatives for music similarity estimation

open access: yes, 2012
One of the popular methods for content-based music similarity estimation is to model timbre with MFCC as a single multivariate Gaussian with full covariance matrix, then use symmetric Kullback-Leibler divergence.
Martinez, Kirk, de leon, Franz
core   +2 more sources

Semi-Supervised Medical Image Classification with Pseudo Labels Using Coalition Similarity Training

open access: yesMathematics
The development of medical image classification models necessitates a substantial number of labeled images for model training. In real-world scenarios, sample sizes are typically limited and labeled samples often constitute only a small portion of the ...
Kun Liu, Shuyi Ling, Sidong Liu
doaj   +1 more source

Home - About - Disclaimer - Privacy