Results 231 to 240 of about 3,548,350 (290)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Structural optimization of drug molecules with incrementally trained language models. [PDF]

Nat Commun
Hörmann T, Mayer D, Lewandowski M, Hunklinger A, Wein T, Merk D.   +5 more
europepmc   +1 more source

Alignment of Large Language Model Responses With Human Therapists in Motivational Interviewing.

JAMA Netw Open
Teferra BG, Huang S, Johny N, Perivolaris A, Al-Shamali H, Parkington K, Rueda A, Zeifman RJ, Sharma D, Krishnan S, Monson C, Bhat V.   +11 more
europepmc   +1 more source

SigRescueR: a pan-system framework for noise correction and mutational signature identification across sequencing platforms. [PDF]

Brief Bioinform
Nguyen PT, Zhivagui M.
europepmc   +1 more source

A tale of two meta-analyses: Similarity, consistency and avoiding overinterpretation in network meta-analysis. [PDF]

J Eur Acad Dermatol Venereol
Shourick J, Garbayo-Salmons P.
europepmc   +1 more source

Prior cocaine use disrupts identification of hidden states by single units and neural ensembles in orbitofrontal cortex. [PDF]

Elife
Zong W, Mueller L, Zhang Z, Zhou J, Schoenbaum G.   +4 more
europepmc   +1 more source

Deep Learning for Content-Based Medical Image Retrieval in Picture Archiving and Communication Systems for Brain Tumor Detection: Algorithm Development and Validation.

JMIR Med Inform
Lee CL, Hsu TH, Wu YT, Guo WY, Chu WC, Lien CY.   +5 more
europepmc   +1 more source