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Population-Level Implications of Parental Similarity for the Prevalence and Heritability of Psychiatric Disorders.

open access: yesJAMA Psychiatry
Dehkordi SR   +13 more
europepmc   +1 more source
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Learning similarity with cosine similarity ensemble

Information Sciences, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Li Zhang, Fanzhang Li
exaly   +2 more sources

Molecular Similarity and Property Similarity

Current Topics in Medicinal Chemistry, 2004
This paper reviews the main efforts undertaken up to date in order to understand, rationalize and apply the similarity principle (similar compounds=>similar properties) as a computational tool in modern drug discovery. The best suited mathematical expression of this classical working hypothesis of medicinal chemistry needs to be carefully chosen (out ...
Frédérique, Barbosa, Dragos, Horvath
openaire   +2 more sources

Similar Names for Similar Biologics

BioDrugs, 2014
Approval of the first biosimilar in the USA may occur by the end of 2014, yet a naming approach for biosimilars has not been determined. Biosimilars are highly similar to their biologic reference product but are not identical to it, because of their structural complexity and variations in manufacturing processes among companies.
Nicole, Casadevall   +3 more
openaire   +2 more sources

Similar donors—similar blood?

Transfusion, 2013
BackgroundRed blood cell (RBC) storage lesions have been suggested as contributing factors to suboptimal clinical outcomes. While undesirable effects of storage are well documented, their clinical relevance is still debated. Focus on storage time as the sole determinant of RBC quality ignores the variability in cell properties that may depend on ...
Michael, Tarasev   +5 more
openaire   +2 more sources

Similarity by Compression

Journal of Chemical Information and Modeling, 2006
We present a simple and effective method for similarity searching in virtual high-throughput screening, requiring only a string-based representation of the molecules (e.g., SMILES) and standard compression software, available on all modern desktop computers.
James L. Melville   +2 more
openaire   +2 more sources

Similarity caching

Proceedings of the twenty-eighth ACM SIGMOD-SIGACT-SIGART symposium on Principles of database systems, 2009
We introduce the similarity caching problem, a variant of classical caching in which an algorithm can return an element from the cache that is similar, but not necessarily identical, to the query element. We are motivated by buffer management questions in approximate nearest-neighbor applications, especially in the context of caching targeted ...
CHIERICHETTI, FLAVIO   +2 more
openaire   +2 more sources

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