Results 261 to 270 of about 1,581,512 (316)

Learning similarity with cosine similarity ensemble

Information Sciences, 2015
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Li Zhang, Fanzhang Li
exaly   +2 more sources

Similar Names for Similar Biologics

BioDrugs, 2014
Approval of the first biosimilar in the USA may occur by the end of 2014, yet a naming approach for biosimilars has not been determined. Biosimilars are highly similar to their biologic reference product but are not identical to it, because of their structural complexity and variations in manufacturing processes among companies.
Nicole, Casadevall, Thomas, Felix, Bruce E, Strober, David G, Warnock   +3 more
openaire   +2 more sources

Molecular Similarity and Property Similarity

Current Topics in Medicinal Chemistry, 2004
This paper reviews the main efforts undertaken up to date in order to understand, rationalize and apply the similarity principle (similar compounds=>similar properties) as a computational tool in modern drug discovery. The best suited mathematical expression of this classical working hypothesis of medicinal chemistry needs to be carefully chosen (out ...
Frédérique, Barbosa, Dragos, Horvath
openaire   +2 more sources

Similar donors—similar blood?

Transfusion, 2013
BackgroundRed blood cell (RBC) storage lesions have been suggested as contributing factors to suboptimal clinical outcomes. While undesirable effects of storage are well documented, their clinical relevance is still debated. Focus on storage time as the sole determinant of RBC quality ignores the variability in cell properties that may depend on ...
Michael, Tarasev, Kenneth, Alfano, Sumita, Chakraborty, Lucia, Light, Kim, Doeden, Jed B, Gorlin   +5 more
openaire   +2 more sources