Results 81 to 90 of about 147,222 (296)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Research on the Serialized Design Criterion and Engineering Application

open access: yes, 2011
The similarity theory and similarity criterion are applied to the series design of non-standard mechanical products. The series design method has been developed by using series design criterion; the similarity criterion of mechanical components or ...
Wei Zhang, Yue Bo, Zhi Hui Lu
core   +1 more source

An objective criterion to evaluate sequence-similarity networks helps in dividing the protein family sequence space.

open access: yes, 2023
The deluge of genomic data raises various challenges for computational protein annotation. The definition of superfamilies, based on conserved folds, or of families, showing more recent homology signatures, allow a first categorization of the sequence ...
Hornung, Bastian Volker Helmut   +3 more
core   +1 more source

Similarity criterion of load reduction technology of launcher muzzle air curtain

open access: yesZhongguo Jianchuan Yanjiu
ObjectiveThe load reduction technology of launcher muzzle air curtain reduces the launch load on an underwater vehicle by injecting air at the launcher muzzle during launching.
Jun XING, Wenhui XIONG, Dong CHENG
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

On the use of clustering and the MeSH controlled vocabulary to improve MEDLINE abstract search [PDF]

open access: yes, 2005
Databases of genomic documents contain substantial amounts of structured information in addition to the texts of titles and abstracts. Unstructured information retrieval techniques fail to take advantage of the structured information available.
Gurrin, Cathal   +3 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A criterion for unitary similarity of upper triangular matrices in general position

open access: yesLinear Algebra and its Applications, 2011
Each square complex matrix is unitarily similar to an upper triangular matrix with diagonal entries in any prescribed order. Let A and B be upper triangular n-by-n matrices that (i) are not similar to direct sums of matrices of smaller sizes, or (ii) are in general position and have the same main diagonal. We prove that A and B are unitarily similar if
Farenick, Douglas   +4 more
openaire   +3 more sources

TEMPERATURE DIAGNOSTICS OF GAS TURBINE ENGINE BEARINGS

open access: yesНаучный вестник МГТУ ГА, 2016
The objective of the current research was to develop methodology for diagnosing industrial gas turbine engine bearings using the standard performance parameters.
R. V. Birukov, Y. V. Kiselev
doaj  

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