Results 81 to 90 of about 21,703 (289)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Similarity of Overlap Functions and Robustness of Fuzzy Reasoning
AxiomsThe overlap function has been extensively utilized across various fields. In this paper, we introduce the concepts of the similarity and δ-equality of overlap functions to measure the degree of similarity between two overlap functions.
Songsong Dai, Qiuchen Ruan
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Parallelizing Set Similarity Joins.
, 2022 One of today's major challenges in data science is to compare and relate data of similar nature. Using the join operation known from relational databases could help solving this problem. Given a collection of records, the join operation finds all pairs of records, which fulfill a user-chosen predicate.
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Scalable Similarity Joins of Tokenized Strings [PDF]
2019 IEEE 35th International Conference on Data Engineering (ICDE), 2019 This work tackles the problem of fuzzy joining of strings that naturally tokenize into meaningful substrings, e.g., full names. Tokenized-string joins have several established applications in the context of data integration and cleaning. This work is primarily motivated by fraud detection, where attackers slightly modify tokenized strings, e.g., names ...
Ahmed Metwally 0001, Chun-Heng Huang
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Top-k similarity join over multi-valued objects
, 2012 The join query is a fundamental tool in many modern application areas including location-based services, geographic information system (GIS), finance and capital markets analysis, etc.
Xu, Jing
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Research & Politics, 2018 What makes states join intergovernmental organizations intended to challenge a hegemon? The China-led Asian Infrastructure Investment Bank (AIIB), founded in June 2015, targets the primacy of the US-led Asian Development Bank (ADB) in the Asia-Pacific ...
Vinícius Rodrigues Vieira
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Efficient exact similarity joins
, 2010 Similarity joins play an important role in many application areas, such as near duplicate Web page detection, data integration and cleaning, record linkage, and pattern recognition. Consequently, there has been much interest in developing efficient algorithms for this fundamental operation.
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