Results 61 to 70 of about 7,953 (261)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
MELODY-JOIN: Efficient Earth Mover’s Distance Similarity Joins Using MapReduce [PDF]
, 2014 —The Earth Mover’s Distance (EMD) similarity join retrieves pairs of records with EMD below a given threshold. It has a number of important applications such as near duplicate image retrieval and pattern analysis in probabilistic datasets.
Rui Zhang +3 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Scalable Similarity Joins of Tokenized Strings [PDF]
2019 IEEE 35th International Conference on Data Engineering (ICDE), 2019 This work tackles the problem of fuzzy joining of strings that naturally tokenize into meaningful substrings, e.g., full names. Tokenized-string joins have several established applications in the context of data integration and cleaning. This work is primarily motivated by fraud detection, where attackers slightly modify tokenized strings, e.g., names ...
Ahmed Metwally 0001, Chun-Heng Huang
openaire +2 more sources
Pushing similarity joins down to the storage layer in XML databases
, 2017 PurposeThis article aims to explore how to incorporate similarity joins into XML database management systems (XDBMSs). The authors aim to provide seamless and efficient integration of similarity joins on tree-structured data into an XDBMS architecture ...
Theo Härder, Leonardo Andrade Ribeiro
core +1 more source
Querying and Merging Heterogeneous Data by Approximate Joins on Higher-Order Terms [PDF]
, 2008 Integrating heterogeneous data from sources as diverse as web pages, digital libraries, knowledge bases, the Semantic Web and databases is an open problem.
Price, S, Flach, PA
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Similarity joins as stronger metric operations
, 2010 Similarity joins between two sets of records return pairs of records whose similarity is no less than a given threshold. More specifically, consider two sets of records, R and S , a similarity ...
Wei Wang
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source