Results 51 to 60 of about 1,243,483 (265)

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

In silico target identification and pharmacokinetic profiling of 2-aryl-quinoline-4-carboxylic acid derivatives as potential antileishmanial agents

Frontiers in Pharmacology
IntroductionLeishmaniasis remains a major neglected tropical disease, and new therapeutic strategies are urgently needed. This study aimed to identify the molecular target of 2-aryl-quinoline-4-carboxylic acid derivatives and assess their pharmacokinetic
Marília Cecília da Silva, Jéssika de Oliveira Viana, Tayná Rodrigues Olegário, Jayne Maria Sabino, Euzébio Guimarães Barbosa, Elton José Ferreira Chaves, Gerd Bruno Rocha, Claudio Gabriel Lima-Junior, Karen Cacilda Weber   +8 more
doaj   +1 more source

Off the Beaten Path: Let's Replace Term-Based Retrieval with k-NN Search

, 2016
Retrieval pipelines commonly rely on a term-based search to obtain candidate records, which are subsequently re-ranked. Some candidates are missed by this approach, e.g., due to a vocabulary mismatch.
Andoni A., Beyer K., Broder A. Z., Brown P. F., Fried D., Le Q., Mikolov T., Mu Y., Muja M., Petrović S., Riezler S., Salton G., Wang J., Weber R., Yang L., Yao X.   +15 more
core   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Protein structural similarity search by Ramachandran codes

BMC Bioinformatics, 2007
Background Protein structural data has increased exponentially, such that fast and accurate tools are necessary to access structure similarity search.
Chang Chih-Hung, Huang Po-Jung, Lo Wei-Cheng, Lyu Ping-Chiang   +3 more
doaj   +1 more source

Flexible aggregate similarity search [PDF]

Proceedings of the 2011 ACM SIGMOD International Conference on Management of data, 2011
Aggregate similarity search, a.k.a. aggregate nearest neighbor (Ann) query, finds many useful applications in spatial and multimedia databases. Given a group Q of M query objects, it retrieves the most (or top-k) similar object to Q from a database P, where the similarity is an aggregation (e.g., sum, max) of the distances between the retrieved object ...
Yang Li, Feifei Li, Ke Yi, Bin Yao, Min Wang   +4 more
openaire   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Development of neoplastic region selection algorithm based on breast cancer whole slide image

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2020
Analysis of breast cancer whole-slide image is an extremely labor-intensive process. Histological whole slide images have the following features: a high degree of tissue diversity both in one image and between different images, hierarchy, a large amount ...
S. N. Rjabceva, V. A. Kovalev, V. D. Malyshev, I. A. Siamionik, M. A. Derevyanko, R. A. Moskalenko, A. S. Dovbysh, T. R. Savchenko, A. N. Romaniuk   +8 more
doaj   +1 more source

Performance Evaluation and Optimization of Math-Similarity Search

, 2015
Similarity search in math is to find mathematical expressions that are similar to a user's query. We conceptualized the similarity factors between mathematical expressions, and proposed an approach to math similarity search (MSS) by defining metrics ...
C Spearman, D Hawking, J Bar-Ilan, L Vaughan, M Kendall, Q Zhang, R Fagin, W Hartmann   +7 more
core   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source