Results 61 to 70 of about 706,541 (289)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Sharing Different Reference Frames: How Stimulus Setup and Task Setup Shape Egocentric and Allocentric Simon Effects

Frontiers in Psychology, 2018
Different reference frames are used in daily life in order to structure the environment. The two-choice Simon task setting has been used to investigate how task-irrelevant spatial information influences human cognitive control.
Pamela Baess, Tom Weber, Christina Bermeitinger   +2 more
doaj   +1 more source

The role of constraints in expert memory [PDF]

, 2003
A great deal of research has been devoted to developing process models of expert memory. However, K. J. Vicente and J. H. Wang (1998) proposed (a) that process theories do not provide an adequate account of expert recall in domains in which memory recall
Gobet, F, Waters, AJ
core   +2 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

The Simon Effect Asymmetry for Left- and Right-Dominant Persons

Journal of Cognition, 2023
When participants respond to a task-relevant stimulus attribute by pressing a left or right key with the respective index finger, reaction time is shorter if task-irrelevant left-right stimulus location corresponds to that of the response key than if it ...
Robert W. Proctor, Qi Zhong, Jing Chen
doaj   +1 more source

Working memory and working attention: What could possibly evolve? [PDF]

, 2010
The concept of “working” memory is traceable back to nineteenth century theorists (Baldwin, 1894; James 1890) but the term itself was not used until the mid-twentieth century (Miller, Galanter & Pribram, 1960).
Beaman, Charles Philip
core   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

The Simon Task and Aging

Medicine & Science in Sports & Exercise, 2014
Purpose This study aimed to investigate the influence of an acute bout of moderate exercise and examine the potential lasting improvements over time in young and old adults within the same experimental paradigm over a 2-h testing period. The study was designed to assess the efficiency of selective control and the propensity to make fast impulsive ...
Joyce, Jennifer, Smyth, Patrick J., Donnelly, Alan E., Davranche, Karen   +3 more
openaire   +3 more sources

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

A Dual-Task Paradigm to Study the Interference Reduction in the Simon Task

Experimental Psychology, 2015
Analyzing RT distributions in the Simon task reveals that congruency effects decrease for the longest RTs. Four experiments were carried out to examine whether this decrease of the congruency effect with response speed was under a top-down control or due to bottom-up mechanisms.
Suarez, Isabel, Vidal, Franck, Burle, Boris, Casini, Laurence   +3 more
openaire   +2 more sources