Results 61 to 70 of about 82,785 (291)

Real-Time Curvature Detection of a Flexible Needle with a Bevel Tip

open access: yesSensors, 2018
As one of the major methods for the diagnosis and treatment of cancers in their early stages, the percutaneous puncture technique has bright prospect in biopsy, ablation, proximity radiotherapy, and drug delivery.
Bo Zhang   +6 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Harmonic and Intermodulation Performance of Nonlinear Electronic Circuits

open access: yesActive and Passive Electronic Components, 1998
A unified technique for mathematical modelling of the input output characteristics of nonlinear electronic circuits is presented. This technique can be easily implemented using simple hand computations without recourse to standard curve-fitting ...
Muhammad Taher Abuelma'atti
doaj   +1 more source

Implementation of a V/f Controlled Variable Speed Induction Motor Drive

open access: yesEmitter: International Journal of Engineering Technology, 2020
DSP implementation of speed control of three phase induction motor drive is presented in this paper. A closed loop speed control has been achieved using constant V/f technique which is a simple scalar control method used to control the magnitude of the ...
Zeynep Bala Duranay   +2 more
doaj   +1 more source

HIGH-RESOLUTION MELTING CURVE (HRM) ANALYSIS IN GENOTYPIC DISCRIMINATION OF CRYPTOSPORIDIUM ISOLATES FROM STOOL OF EGYPTIAN CHILDREN [PDF]

open access: yesJournal of the Egyptian Society of Parasitology, 2018
Cryptosporidiosis is a recognized child infectious killer and the second cause of diarrheal disease and death in infants. Assessing Cryptosporidium spp.
MONA KHATER   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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