Results 41 to 50 of about 172,916 (261)

Pupillometry as a reliable metric of auditory detection and discrimination across diverse stimulus paradigms in animal models

Scientific Reports, 2021
Estimates of detection and discrimination thresholds are often used to explore broad perceptual similarities between human subjects and animal models.
Pilar Montes-Lourido, Manaswini Kar, Isha Kumbam, Srivatsun Sadagopan   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Tests of Racial Discrimination in a Simple Financial Market: Managers in Major League Baseball

International Journal of Financial Studies, 2018
This study tests for racial discrimination against minority managers in Major League Baseball using financial-market imbalances as it relates to the wagering marketplace for the sport.
Rodney Paul, Andrew Weinbach, Justin Mattingly   +2 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Emergent Relations after Teaching Textual Responses with Simple Discrimination Procedure in Children

Psicologia, 2010
The repertoire of reading with comprehension has been found during emergent relations tests after teaching with conditional discrimination procedure.
Heloísa Cursi Campos, Nilza Micheletto
doaj  

Impact of simple substitution methods for missing data on Classical test theory difficulty and discrimination [PDF]

Tutorials in Quantitative Methods for Psychology, 2018
In Classical test theory, difficulty ($p$) and discrimination ($d$) are two item coefficients that are widely used to analyze and validate items in educational testing.
Béland, Sébastien, Jolani, Shahab, Pichette, Fran{\c {c}}ois, Renaud, Jean-Sébastien   +3 more
doaj   +1 more source

A Simple Implementation of the Stochastic Discrimination for Pattern Recognition [PDF]

, 2000
The method of stochastic discrimination (SD) introduced by Kleinberg ([6,7])is a new method in pattern recognition. It works by producing weak classifiers and then combining them via the Central Limit Theorem to form a strong classifier. SD is overtraining-resistant, has a high convergence rate, and can work quite well in practice. However, some strict
Dechang Chen, Xiuzhen Cheng
openaire   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

A simple method for algal species discrimination in East China Sea, using multiple satellite imagery

Geoscience Letters, 2022
Satellites can help monitor harmful algal blooms in coastal regions. Methods have been developed using different satellite missions. However, it is necessary to develop a simple and useful method for discriminating harmful algal species that could be ...
Chi Feng, Joji Ishizaka, Shengqiang Wang
doaj   +1 more source