Results 41 to 50 of about 1,361,110 (264)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
LOCALLY NORMAL SUBGROUPS OF TOTALLY DISCONNECTED GROUPS. PART II: COMPACTLY GENERATED SIMPLE GROUPS
Forum of Mathematics, Sigma, 2017 We use the structure lattice, introduced in Part I, to undertake a systematic study of the class $\mathscr{S}$ consisting of compactly generated ...
PIERRE-EMMANUEL CAPRACE +2 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Characterization of A5 and PSL(2,7) by sum of elements orders [PDF]
International Journal of Group Theory, 2013 Let $G$ be a finite group. We denote $psi(G)=sum_{gin G}o(g)$ where $o(g)$ denotes the order of $g in G$. Here we show that $psi(A_5)< psi(G)$ for every nonsimple group $G$ of order 60. Also we prove that $psi(PSL(2,7))groups $G$ of order 168.
Seyyed Majid Jafarian Amiri
doaj
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Abelian supplements in almost simple groups
Forum of Mathematics, SigmaLet G be an almost simple group with socle $G_0$ . In this paper we prove that whenever $G/G_0$ is abelian, then there exists an abelian subgroup A of G such that $G=AG_0$ .
Mauro Costantini +2 more
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On the number of connected components of divisibility graph for certain simple groups [PDF]
Transactions on Combinatorics, 2016 The divisibility graph D(G) D(G) for a finite group G G is a graph with vertex set cs(G)∖{1} cs(G)∖{1} where cs(G) cs(G) is the set of conjugacy class sizes of G G. Two vertices a a and b b are adjacent whenever a a divides b b or b b divides a a.
Adeleh Abdolghafourian +1 more
doaj
Quantitative characterization of finite simple groups: a complement [PDF]
International Journal of Group TheoryIn this paper, we summarize the research on the characterization of finite simple groups and the study of finite groups based on their ``set of element orders" and ``two orders" (the order of the group and the set of element orders). We also discuss some
Wujie Shi
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
On derangements in simple permutation groups
Forum of Mathematics, SigmaLet $G \leqslant \mathrm {Sym}(\Omega )$ be a finite transitive permutation group and recall that an element in G is a derangement if it has no fixed points on $\Omega $ . Let $\Delta (G)$ be the set of derangements in G and define
Timothy Burness, Marco Fusari
doaj +1 more source