Results 51 to 60 of about 1,004,597 (279)

Counting submodules of a module over a noetherian commutative ring

, 2019
We count the number of submodules of an arbitrary module over a countable noetherian commutative ring. We give, along the way, a structural description of meager modules, which are defined as those that do not have the square of a simple module as ...
Cornulier, Yves
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

A simple and highly efficient flyback inverter control strategy for AC module application

IET Power Electronics, 2023
A simple and efficient control structure of a flyback converter is proposed in this paper considering its intrinsic dynamic characteristics. The proposed control strategy makes use of a PI controller with a low pass filter to overcome the limitations on ...
Saleh Mohammadi, Hamid Reza Izadfar, Naser Eskandarian   +2 more
doaj   +1 more source

On a generic Verma module at the critical level over affine Lie superalgebras

, 2007
We describe the structure of a Verma module with a generic highest weight at the critical level over a symmetrizable affine Lie superalgebra not of the type A(2k,2l)^{(4)}. We obtain the character formula for a simple module with a generic highest weight
Arakawa, Chari, Deodhar, Feigin, Frenkel, Goodman, Gorelik, Gorelik, Hayashi, Hoyt, Jantzen, Kac, Kac, Kac, Ku, Maria Gorelik, Mathieu, Penkov, Serganova, Szczesny, van de Leur, Wakimoto, Wakimoto, Wallach   +23 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Idempotent Reflexive rings whose every simle singular right module are yj-injective [PDF]

المجلة العراقية للعلوم الاحصائية, 2011
In this paper we study rightidempotent reflexive ring whose simple singular right R-module isYJ-injective, we prove that this type of ring is right weakly regular ring, we show that if R is N duo or NCI ring and R is right idempotent reflexive ring ...
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Semiprime SF-rings whose essential left ideals are two-sided

International Journal of Mathematics and Mathematical Sciences, 1994
It is proved that if R is a semiprime ELT-ring and every simple right R-module is flat then R is regular. Is R regular if R is a semiprime ELT-ring and every simple right R-module is flat? In this note, we give a positive answer to the question.
Zhang Jule, Du Xhianneng
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source