Results 71 to 80 of about 123,484 (298)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Developing young learners’ reading competence in Ethiopia: A critical review of the Ministry of Education’s guidelines for developing supplementary reading materials

Bahir Dar Journal of Education
This study presents a critical review of the official guidelines established in 2016 by the Ethiopian Ministry of Education offering detailed criteria for the development and selection of supplementary reading materials (SRMs) for primary school ...
Samuel Belayneh Kame, Mulugeta Tarekegne Tsegaye, Mona Evelyn Flognfeldt, Margareth Sandvik   +3 more
doaj   +1 more source

The Shift from High to Liquid Ideals: Making Sense of Journalism and Its Change through a Multidimensional Model

Nordicom Review, 2020
By reading qualitative studies, surveys, organisational histories, and textbooks, one can claim that the ethos of journalists has undergone fundamental changes in recent decades.
Koljonen Kari
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Läsa normalt

Tidskrift för Litteraturvetenskap, 2010
Reading »Normal«: A Critique of Rosenblatt’s Reader-Response Theory In the article we address the question of how the relation between literary theory and literary didactics should be understood.
Peter Degerman, Anders Johansson
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Braille in the Sighted: Teaching Tactile Reading to Sighted Adults.

PLoS ONE, 2016
Blind people are known to have superior perceptual abilities in their remaining senses. Several studies suggest that these enhancements are dependent on the specific experience of blind individuals, who use those remaining senses more than sighted ...
Łukasz Bola, Katarzyna Siuda-Krzywicka, Małgorzata Paplińska, Ewa Sumera, Paweł Hańczur, Marcin Szwed   +5 more
doaj   +1 more source

The simple view of reading in elementary school: A systematic review

Revista de Logopedia, Foniatría y Audiología, 2014
Resumen basado en la publicación Resumen en español Se presenta un estudio en el que se revisaron cincuenta y seis investigaciones en las que se incluían los tres componentes de la Concepción Simple de la Lectura (CSL) en alumnos de educación primaria hablantes de inglés.
Anny Castilla-Earls, Juan Cruz Ripoll Salceda, Gerardo Aguado Alonso   +2 more
openaire   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

legere discitur legendo: extensive reading in the Latin classroom

The Journal of Classics Teaching, 2019
As a Latin teacher, I think a lot about reading. Without texts I would not have a subject to teach, and the goal of many Latin programs (including my own) is teaching students to read Latin texts.
Andrew Olimpi
doaj   +1 more source