Results 71 to 80 of about 1,694,267 (336)

Irony's architecture: Reflections on a photographic research project [PDF]

, 2007
This paper presents a research approach based on irony, rather than certainty. Using Richard Rorty's conception of irony, we contend that much traditional research in management presents a final language which is implicit in both the construction of a ...
Bathurst, Ralph, Sayers, Janet, Symonds, Henry   +2 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Developing young learners’ reading competence in Ethiopia: A critical review of the Ministry of Education’s guidelines for developing supplementary reading materials

Bahir Dar Journal of Education
This study presents a critical review of the official guidelines established in 2016 by the Ethiopian Ministry of Education offering detailed criteria for the development and selection of supplementary reading materials (SRMs) for primary school ...
Samuel Belayneh Kame, Mulugeta Tarekegne Tsegaye, Mona Evelyn Flognfeldt, Margareth Sandvik   +3 more
doaj   +1 more source

Love on the Veldt: Romance and Ideology in Gertrude Page’s ‘A Terror That Saved’ (1912)

NJES: Nordic Journal of English studies, 2017
The following essay offers a close reading of an obscure imperial short story, Gertrude Page’s ‘A Terror That Saved’ (1912), in order to question the assumptions that short fiction about imperial adventure is necessarily masculine, and that short ...
Stephen Donovan
doaj   +1 more source

Searching for Dr Johnson: the digitisation of the Burney Newspaper Collection [PDF]

, 2018
No abstract ...
Prescott, Andrew
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The Shift from High to Liquid Ideals: Making Sense of Journalism and Its Change through a Multidimensional Model

Nordicom Review, 2020
By reading qualitative studies, surveys, organisational histories, and textbooks, one can claim that the ethos of journalists has undergone fundamental changes in recent decades.
Koljonen Kari
doaj   +1 more source

The Radical Account of Bare Plural Generics [PDF]

, 2020
Bare plural generic sentences pervade ordinary talk. And yet it is extremely controversial what semantics to assign to such sentences. In this paper, I achieve two tasks.
Nguyen, Anthony
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Läsa normalt

Tidskrift för Litteraturvetenskap, 2010
Reading »Normal«: A Critique of Rosenblatt’s Reader-Response Theory In the article we address the question of how the relation between literary theory and literary didactics should be understood.
Peter Degerman, Anders Johansson
doaj   +1 more source