Results 181 to 190 of about 91,721 (300)

Reliability measures in knowledge structure theory

open access: yesBritish Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract In knowledge structure theory (KST) framework, this study evaluates the reliability of knowledge state estimation by introducing two key measures: the expected accuracy rate and the expected discrepancy. The accuracy rate quantifies the likelihood that the estimated knowledge state aligns with the true state, while the expected discrepancy ...
Debora de Chiusole   +3 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

open access: yesBritish Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu   +6 more
wiley   +1 more source

Oncolytic Vaccinia Virus‐HSP70‐shRNA Amplifies Viral Replication, ROS/Autophagy, and Immunity to Fight Colorectal Cancer

open access: yesCancer Science, EarlyView.
OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan   +8 more
wiley   +1 more source

تحسینات الطریقــة الفردیـــة المتوازیــــة

open access: yesAl-Rafidain Journal of Computer Sciences and Mathematics, 2005
Bashir M. Salih, Muhammad W.M. Ali
doaj   +1 more source

Triple‐Mutated HSV‐1 Expressing Soluble B7‐1 Plus CTLA‐4 Blockade Suppresses Lymph Node Metastasis in Tongue Cancer

open access: yesCancer Science, EarlyView.
In murine tongue cancer models, T‐mB7‐1, a triple‐mutated oncolytic herpes simplex virus type 1 (HSV‐1) engineered to express soluble B7‐1, suppresses cervical lymph node metastasis and improves survival, addressing a major prognostic determinant in oral squamous cell carcinoma (OSCC).
Akinari Sugauchi   +11 more
wiley   +1 more source

Optimal Smoothed Analysis of the Simplex Method

open access: yes
International audienceSmoothed analysis is a method for analyzing the performance of algorithms, used especially for those algorithms whose running time in practice is significantly better than what can be proven through worst-case analysis. Spielman and
Bach, Eleon, Huiberts, Sophie
core  

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