Results 91 to 100 of about 3,382,528 (291)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Numerical simulation on seismic pounding damage in a simply-supported steel bridge. [PDF]
Heliyon, 2023 Shi F, Wang D, Tong L, Tang W.
europepmc +1 more source
Wheel-Rail Contact Forces in High-Speed Simply Supported Bridges at Resonance [PDF]
, 2004 The response of high-speed bridges at resonance, particularly under flexural vibrations, constitutes a subject of research for many scientists and engineers at the moment.
Alarcón Álvarez, Enrique +2 more
core
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Simply-Supported Elliptical Auxetic Plates
Journal of Mechanics, 2015 AbstractWhile the maximum bending moment, and hence maximum bending stress, of a fully clamped elliptical plate under uniform load is independent from the Poisson's ratio of the plate material, the same cannot be said so when the plate is simply supported.
openaire +1 more source
Structural health monitoring methodology for simply supported bridges: numerical implementation
Revista Facultad de Ingeniería Universidad de Antioquia, 2007 El monitoreo de daño en estructuras civiles está recibiendo actualmente gran interés por parte de investigadores debido al gran impacto económico e implicaciones de seguridad relacionadas con una temprana detección de daño estructural.
Carlos Alberto Riveros Jerez
doaj
MachinesThis paper presents theoretical studies on the vibration control of an elastic beam using a lever-type dynamic vibration absorber (Lever-Type DVA). The simply supported beam is adopted as the primary system to investigate the suppression mechanism and ...
Yafeng Liu, Yongjun Shen, Ruiliang Zhang
doaj +1 more source
The response of a simply supported plate to transient forces. Part 2 - The effect of N-waves at oblique incidence [PDF]
Effect of N waves at oblique incidence on response of simply supported plate to transient ...
Craggs, A.
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source