Results 181 to 190 of about 1,152,910 (296)

Protection of Anthocyanins by Food Matrix During Simulated Digestion: Comparative Analysis of Whole-Açaí Powder and Extracts. [PDF]

Foods
Kumkum R, Aston-Mourney K, McNeill BA, Rivera LR.   +3 more
europepmc   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

In Vitro Simulated Digestion Unveils the Multifunctional Benefits of Freeze-Dried Cowpea Fiber: Prebiotic, Hypoglycemic, Antioxidant Activity, and Postbiotic-Mediated Anti-Inflammatory Effects. [PDF]

ACS Omega
Sonklin C, Limsumphan S, Srisuwan N, Bunphueak P, Rungsardthong V, Pornwongthong P, Tabtimmai L, Sedtananun S, Thumthanaruk B.   +8 more
europepmc   +1 more source

Effects of Processing Conditions and Simulated Digestion In Vitro on the Antioxidant Activity, Inhibition of Xanthine Oxidase and Bioaccessibility of Epicatechin Gallate. [PDF]

Foods, 2023
Zhu M, Fei X, Gong D, Zhang G.
europepmc   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

Ultrasound pretreatment and fermentation temperature improve phytochemical, antioxidant capacity, and mineral bioaccessibility in tempeh under simulated digestion. [PDF]

Ultrason Sonochem
Harahap IA, Suliburska J, Weber D, Esatbeyoglu T.   +3 more
europepmc   +1 more source

Insight into the phenolics and antioxidant activity of Indian jujube (Ziziphus mauritiana Lamk) peel and pulp subjected to the simulated digestion. [PDF]

Heliyon, 2023
Wang ZT, Liu YP, Ma YL, Pan SY, Li JK, Shi SJ, Wu ZF, Li Z, Shang YF, Wei ZJ.   +9 more
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Prediction Equations of Growth Performance and Metabolizable Energy From in Vitro Digestible Energy Determined With a Computer-Controlled Simulated Digestion System in Feed for Chickens. [PDF]

Anim Sci J
Niu G, Zhang Y, Zhang T, Yang L, Xiang B, Tao L.   +5 more
europepmc   +1 more source

Effect of geographical location, processing and simulated digestion on antioxidant characteristics of quince (Cydonia oblonga). [PDF]

Heliyon, 2022
Baroni MV, Fabani MP, Adan F, Podio NS, Wunderlin DA.   +4 more
europepmc   +1 more source