Results 201 to 210 of about 17,651 (246)

Secondary metabolism in simulated microgravity

The Chemical Record, 2001
AbstractWe have studied microbial secondary metabolism in a simulated microgravity (SMG) environment provided by NASA rotating‐wall bioreactors (RWBs). These reactors were designed to simulate some aspects of actual microgravity that occur in space. Growth and product formation were observed in SMG in all cases studied, i.e., Bacillus brevis produced ...
A L, Demain, A, Fang
openaire   +2 more sources

Simulated microgravity (SMG) and bacteria.

Rivista di biologia, 2003
This past century has been a scientific revolution in the understanding of the cell as the basic unit of life. However an immense paucity of knowledge exists on microbial growth, survival, function and structure in space. However, there are significant constraints placed on conducting biological research in space such as time, available stowage space ...
Huitema, Carly, Baudette, Lee A., Trevors, Jack T.   +2 more
openaire   +2 more sources

Simulated microgravity accelerates aging in Saccharomyces cerevisiae

Life Sciences in Space Research, 2021
The human body experiences physiological changes under microgravity environment that phenocopy aging on Earth. These changes include early onset osteoporosis, skeletal muscle atrophy, cardiac dysfunction, and immunosenescence, and such adaptations to the space environment may pose some risk to crewed missions to Mars.
Ana Paula Montanari, Fukuda, Vittoria de Lima, Camandona, Kelliton José Mendonça, Francisco, Rafaela Maria, Rios-Anjos, Claudimir, Lucio do Lago, Jose Ribamar, Ferreira-Junior   +5 more
openaire   +2 more sources

Simulation of blood flow in microgravity

The American Journal of Surgery, 1992
Knowledge of venous, capillary, and arterial blood flow in microgravity is required to modify hemostatic techniques for control of bleeding in traumatic injuries or surgical procedures in space. To simulate human arterial, venous, and capillary bleeding, fresh whole bovine blood was injected by two operators at calculated flow rates (3.5, 7, and 14 mL ...
K, McCuaig, C W, Lloyd, J, Gosbee, W W, Snyder   +3 more
openaire   +2 more sources

Neurophysiological adaptations to spaceflight and simulated microgravity

Clinical Neurophysiology, 2021
Changes in physiological functions after spaceflight and simulated spaceflight involve several mechanisms. Microgravity is one of them and it can be partially reproduced with models, such as head down bed rest (HDBR). Yet, only a few studies have investigated in detail the complexity of neurophysiological systems and their integration to maintain ...
Buoite Stella A., Ajcevic M., Furlanis G., Manganotti P.   +3 more
openaire   +4 more sources

Stem Cell Culture Under Simulated Microgravity

2020
Challenging environment of space causes several pivotal alterations in living systems, especially due to microgravity. The possibility of simulating microgravity by ground-based systems provides research opportunities that may lead to the understanding of in vitro biological effects of microgravity by eliminating the challenges inherent to spaceflight ...
Muge, Anil-Inevi, Oyku, Sarigil, Melike, Kizilkaya, Gulistan, Mese, H Cumhur, Tekin, Engin, Ozcivici   +5 more
openaire   +2 more sources

Validity of microgravity simulation models on Earth

American Journal of Kidney Diseases, 2001
Many studies have used water immersion and head-down bed rest as experimental models to simulate responses to microgravity. However, some data collected during space missions are at variance or in contrast with observations collected from experimental models. These discrepancies could reflect incomplete knowledge of the characteristics inherent to each
Regnard, J, Heer, M, Drummer, C, Norsk, P   +3 more
openaire   +4 more sources

Bacillus thuringiensisConjugation in Simulated Microgravity

Astrobiology, 2009
Spaceflight experiments have suggested a possible effect of microgravity on the plasmid transfer among strains of the Gram-positive Bacillus thuringiensis, as opposed to no effect recorded for Gram-negative conjugation. To investigate these potential effects in a more affordable experimental setup, three ground-based microgravity simulators were tested:
Elise, Beuls, Rob, Van Houdt, Natalie, Leys, Camelia, Dijkstra, Oliver, Larkin, Jacques, Mahillon   +5 more
openaire   +2 more sources

Simulated microgravity upregulates an endothelial vasoconstrictor prostaglandin

Journal of Applied Physiology, 2001
Endothelial nitric oxide contributes to the vascular hyporesponsiveness to norepinephrine (NE) observed in carotid arteries from rats exposed to simulated microgravity. The goal of the present study was to determine whether a cyclooxygenase product of arachidonic acid also influences vascular responsiveness in this setting.
D S, Sangha, S, Han, R E, Purdy
openaire   +2 more sources

GASTROINTESTINAL FUNCTION IN SIMULATED SPACE FLIGHT MICROGRAVITY

Digestive and Liver Disease, 2009
S140 P. Iovino 1, G. Bilancio 2, R. Tortora1, C. Bucci 1, A. Pascariello 1 , M. Siniscalchi 1 , C. Ciacci ∗ ,1 1Università Federico II, Napoli; 2Nefrologia Seconda Università, Napoli Background and aim: Head-down bed rest condition (HDBR) is a microgravity model simulating condition of space flight.
IOVINO, Paola, BILANCIO, GIANCARLO, Tortora R, BUCCI, CRISTINA, Pascariello A, Siniscalchi M, CIACCI, Carolina   +6 more
openaire   +4 more sources