Unanchored simulated treatment comparison on survival outcomes using parametric and Royston-Parmar models with application to lenvatinib plus pembrolizumab in renal cell carcinoma [PDF]
BMC Medical Research MethodologyBackground Population-adjusted indirect comparison using parametric Simulated Treatment Comparison (STC) has had limited application to survival outcomes in unanchored settings.
Christopher G. Fawsitt +4 more
doaj +2 more sources
P1059: COMPARATIVE EFFICACY OF FEDRATINIB AND PACRITINIB FOR THE TREATMENT OF MYELOFIBROSIS IN PATIENTS WITH LOW PLATELET COUNTS: A SIMULATED TREATMENT COMPARISON STUDY [PDF]
HemaSphere, 2022 G. Tremblay +4 more
doaj +2 more sources
Clinical Efficacy of Sarilumab Versus Upadacitinib Over 12 weeks: An Indirect Treatment Comparison
Rheumatology and Therapy, 2023 Introduction The efficacy of sarilumab and upadacitinib, in combination with disease-modifying antirheumatic drugs (DMARDs), was demonstrated in phase 3 clinical trials of patients with rheumatoid arthritis (RA) refractive to previous biologic DMARDs. In
Thomas Huizinga +10 more
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Implementation of Monte Carlo based PET verification of ion beam delivery into a TPS
Radiation Medicine and Protection, 2022 Objective: To develop and implement an ion beam teletherapy verification system based upon simulations of induced radioactivity and comparison with patient positron emission tomography (PET) scans.
Pablo Yepes +7 more
doaj +1 more source
CD44 expression changes in MDA-MB-231 cell line of breast cancer after exposure to 2-D clinorotation [PDF]
فصلنامه علوم و فناوری فضایی, 2021 Studies have shown that simulated microgravity (SMG) affects tumor cell growth and metastasis. However, the underlying molecular basis is still not known.
Zahra Hajebrahimi, Maryam Salavatifar
doaj +1 more source
Application of HIPEC simulations for optimizing treatment delivery strategies
International Journal of Hyperthermia, 2023 Introduction Hyperthermic IntraPEritoneal Chemotherapy (HIPEC) aims to treat microscopic disease left after CytoReductive Surgery (CRS). Thermal enhancement depends on the temperatures achieved.
Daan R. Löke +8 more
doaj +1 more source
Paradigm shift in radiation treatment planning over multiple treatment modalities
Journal of Medical Physics, 2021 The inverse planning simulated annealing optimization engine was used to develop a new method of incorporating biological parameters into radiation treatment planning.
Benjamin Insley +2 more
doaj +1 more source
GEANT4 Simulation of Photoneutron Spectrum from Medical Linear Accelerator
Quantum Beam Science, 2023 Photons with energy totaling more than 10 MeV provide efficient treatment for deeply seated tumors but interact with the nuclei of high-Z materials constituting a head of the linac.
Alexander Chernyaev +3 more
doaj +1 more source
Physics and Imaging in Radiation Oncology, 2022 Background and purpose: Deep learning (DL) provides high sensitivity for detecting and identifying errors in pre-treatment radiotherapy quality assurance (QA).
Cecile J.A. Wolfs, Frank Verhaegen
doaj +1 more source
Allelopathic Potential of Hemp: Implications for Integrated Weed Management
Frontiers in Agronomy, 2022 Evolved resistance to herbicides necessitates alternative weed control strategies. Allelopathic crops show promise as an alternative to exogenous herbicides and could be used to reduce establishment, growth, and reproduction of weeds.
Avery Shikanai +3 more
doaj +1 more source