Results 51 to 60 of about 13,896,786 (311)
, 2016 Comparison of (A) simulated and observed [25] probabilities of fipronil-induced mortality of adults obtaining a blood meal the indicated number of days post-treatment, and (B) simulated and observed [25] fipronil-induced mortality rates of larvae exposed
William E. Grant (329206) +2 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Population-adjusted treatment comparisons: estimates based on Matching-Adjusted Indirect Comparison and Simulated Treatment Comparison [PDF]
, 2017 We present the findings and recommendations of a recent NICE Technical Support Document (available from http://www.nicedsu.org.uk/) regarding the use of population-adjusted treatment comparisons in health technology appraisal.Standard methods for indirect comparisons and network meta-analysis are based on aggregate data, with the key assumption that ...
Phillippo, David +5 more
openaire
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Comparative analysis of numerical solutions of 2D unsteady dambreak waves using FVM and SPH method
Journal of Hydrology and Hydromechanics, 2023 This work presents a comparison of two-dimensional numerical solutions of unsteady free surface flow. This is a simulation of the dam-break wave with different configurations using based-mesh finite volume method and meshless smoothed particle ...
Rahou Ibrahim, Korichi Khaled
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
International Journal of Hyperthermia, 2023 Objective Magnetic nanowires (MNWs) are potential candidates for heating in biomedical applications that require rapid and uniform heating rates, such as warming cryopreserved organs and hyperthermia treatment of cancer cells.
Yicong Chen, Bethanie J.H. Stadler
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Comparison between the measured and simulated erosion.
, 2016 Comparison between the measured and simulated erosion.
Lulu Ren (2286637) +3 more
core +1 more source