Results 51 to 60 of about 1,401,410 (172)

Study of histopathological and molecular changes of rat kidney under simulated weightlessness and resistance training protective effect. [PDF]

PLoS ONE, 2011
To explore the effects of long-term weightlessness on the renal tissue, we used the two months tail suspension model to simulate microgravity and investigated the simulated microgravity on the renal morphological damages and related molecular mechanisms.
Ye Ding, Jun Zou, Zhili Li, Jijing Tian, Saed Abdelalim, Fang Du, Ruiping She, Desheng Wang, Cheng Tan, Huijuan Wang, Wenjuan Chen, Dongqiang Lv, Lingling Chang   +12 more
doaj   +1 more source

Evaluation of Simulated Weightlessness Model of Hindlimb Unloading Miniature Pigs and Their Tissue Damage

Shiyan dongwu yu bijiao yixue
Objective To establish a weightlessness simulation animal model using miniature pigs, leveraging the characteristic of multiple systems’ tissue structures and functions similar to those of humans, and to observe pathophysiological changes, providing a ...
TU Yingxin, JI Yilan, WANG Fei, YANG Dongming, WANG Dongdong, SUN Zhixin, DAI Yuexin, WANG Yanji, KAN Guanghan, WU Bin, ZHAO Deming, YANG Lifeng   +11 more
doaj   +1 more source

Investigating the effect of zinc supplementation on preventing bone resorption in a weightlessness animal model: An experimental study [PDF]

فصلنامه ابن سینا
Background and aims: Bone biomarkers, such as bone-specific alkaline phosphatase (BAP) and osteocalcin (OC), are crucial for researching and monitoring the effects of therapeutic interventions.
Reza Eslami, Amir Khoshvaghti, Kamyab Alizadeh   +2 more
doaj  

Simulated microgravity triggers epithelial mesenchymal transition in human keratinocytes

Scientific Reports, 2017
The microgravitational environment is known to affect the cellular behaviour inducing modulation of gene expression and enzymatic activities, epigenetic modifications and alterations of the structural organization. Simulated microgravity, obtained in the
Danilo Ranieri, Sara Proietti, Simona Dinicola, Maria Grazia Masiello, Benedetta Rosato, Giulia Ricci, Alessandra Cucina, Angela Catizone, Mariano Bizzarri, Maria Rosaria Torrisi   +9 more
doaj   +1 more source

Comparison of Microgravity Analogs to Spaceflight in Studies of Plant Growth and Development

Frontiers in Plant Science, 2019
Life on Earth has evolved under the influence of gravity. This force has played an important role in shaping development and morphology from the molecular level to the whole organism. Although aquatic life experiences reduced gravity effects, land plants
John Z. Kiss, Chris Wolverton, Sarah E. Wyatt, Karl H. Hasenstein, Jack J.W.A. van Loon, Jack J.W.A. van Loon, Jack J.W.A. van Loon   +6 more
doaj   +1 more source

Resistance exercise training improves disuse-induced skeletal muscle atrophy in humans: a meta-analysis of randomized controlled trials

BMC Musculoskeletal Disorders
Background This meta-analysis aimed to determine whether resistance exercise training (RET) can attenuate the loss of muscle volume and function in anti-gravitational muscles, especially quadriceps and calf muscles, during immobilization/disuse ...
Xian Guo, Yanbing Zhou, Xinxin Li, Jinhao Mu   +3 more
doaj   +1 more source

6 Degrees Of Freedom Weightless Simulator

, 1997
6 Degrees of Freedom Weightless ...
openaire   +1 more source

Effect of transcranial laser irradiation on avoidance memory impairments and social interaction induced by simulated weightlessness in Balb/c male mice

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī
Background and Objective: Weightlessness or microgravity represents one of the major challenges of long-duration space missions, exerting profound and sometimes irreversible effects on astronauts’ neurophysiological and psychological functions ...
Seyed Zanyar Athari, Saeed Sadigh-Eteghad, Javad Mahmoudi, Fereshteh Farajdokht   +3 more
doaj  

Angelicae dahuricae radix alleviates simulated microgravity induced bone loss by promoting osteoblast differentiation

npj Microgravity
Bone loss caused by long-duration spaceflight seriously affects the skeletal health of astronauts. There are many shortcomings in currently available treatments for weightlessness-induced bone loss.
Xuechao Liang, Shanfeng Jiang, Peihong Su, Chong Yin, Wei Jiang, Junhong Gao, Zhiyong Liu, Yuhang Li, Weisi Wang, Airong Qian, Ye Tian   +10 more
doaj   +1 more source

Integration of Proteomic and Metabolomic Data Reveals the Lipid Metabolism Disorder in the Liver of Rats Exposed to Simulated Microgravity

Biomolecules
Long-term exposure to microgravity is considered to cause liver lipid accumulation, thereby increasing the risk of non-alcoholic fatty liver disease (NAFLD) among astronauts.
Mengyao Ru, Jun He, Yungang Bai, Kun Zhang, Qianqian Shi, Fang Gao, Yunying Wang, Baoli Li, Lan Shen   +8 more
doaj   +1 more source