Results 31 to 40 of about 250,324 (265)

MOVING SHIP DETECTION AND MOVEMENT PREDICTION IN REMOTE SENSING VIDEOS [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2020
With the rapid development of remote sensing technology, it is possible to obtain continuous video data from outer space successfully. It is of great significance in military and civilian fields to detect moving objects from the remote sensing image ...
Y. Wang   +8 more
doaj   +1 more source

Simulation optimization: a review of algorithms and applications [PDF]

open access: yesAnnals of Operations Research, 2014
Simulation Optimization (SO) refers to the optimization of an objective function subject to constraints, both of which can be evaluated through a stochastic simulation. To address specific features of a particular simulation---discrete or continuous decisions, expensive or cheap simulations, single or multiple outputs, homogeneous or heterogeneous ...
Satyajith Amaran   +3 more
openaire   +6 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Multiple strut-deformation patterns based analytical elastic modulus of sandwich BCC lattices

open access: yesMaterials & Design, 2019
This paper proposed an analytical methodology to predict the mechanical properties of sandwich body-centred cubic (BCC) lattice structures. Based on the Timoshenko beam theory, the multiple strut-deformation patterns were first introduced in the ...
Yunhui Yang   +4 more
doaj   +1 more source

Fuzzy Simheuristics: Solving Optimization Problems under Stochastic and Uncertainty Scenarios

open access: yesMathematics, 2020
Simheuristics combine metaheuristics with simulation in order to solve the optimization problems with stochastic elements. This paper introduces the concept of fuzzy simheuristics, which extends the simheuristics approach by making use of fuzzy ...
Diego Oliva   +5 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A Novel Simulated-Annealing Based Electric Bus System Design, Simulation, and Analysis for Dehradun Smart City

open access: yesIEEE Access, 2020
Smart transportation network development with environmental issues into consideration has brought Industry 4.0 based solutions on priority. In this direction, battery-powered electric bus systems have been considered widely for ensuring flexibility ...
Adarsh Kumar   +5 more
doaj   +1 more source

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