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Results 111 to 120 of about 6,077,636 (282)

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti +19 more
wiley +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner +14 more
wiley +1 more source

A Web Services Component Discovery and Deployment Architecture for Simulation Model Reuse [PDF]

, 2006
CSPs are widely used in industry, although have yet to operate across organizational boundaries. Reuse across organizations is restricted by the same semantic issues that restrict the inter-organization use of web services. The current representations of
Bell, D +4 more
core

Evaluation of a novel EHR sidecar application to display RA clinical outcomes during clinic visits: results of a stepped‐wedge cluster randomized pragmatic trial

Arthritis Care &Research, Accepted Article.
Objective We developed a novel EHR sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk +16 more
wiley +1 more source

Development and Optimization of a Micro-Baffle for the Enhancement of Heat Transfer in Film Boiling

Energies
This study represents the development and optimization of a micro-baffle design to enhance heat transfer in film boiling. Numerical simulations are performed using an open-source computational fluid dynamics (CFD) model, which incorporates the Lee model ...
Onur Muhammed Sarikaya +3 more
doaj +1 more source

An empirical learning-based validation procedure for simulation workflow

, 2018
Simulation workflow is a top-level model for the design and control of simulation process. It connects multiple simulation components with time and interaction restrictions to form a complete simulation system.
Lai, Liyuanjun, Liu, Zhuqing, Zhang, Lin
core

MYCOPHENOLATE MOFETIL TREATMENT REDUCES THE RISK OF TREATMENT ESCALATION DUE TO VASCULAR COMPLICATIONS IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS: EMULATION OF A TARGET TRIAL FROM ITALIAN RHEUMATOLOGY SOCIETY SPRING REGISTRY

Arthritis Care &Research, Accepted Article.
Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis +77 more
wiley +1 more source

Differential Item Functioning on the Patient Health Questionnaire‐8 by Disease Subtype, Language, Sex, and Age among People with Systemic Sclerosis: A Scleroderma Patient‐centered Intervention Network Cohort Study

Arthritis Care &Research, Accepted Article.
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +109 more
wiley +1 more source

VR Simulation-Based vs Traditional Apprenticeship Training in Gynecological Laparoscopy: A Comparative Survey of Residents’ Expectations, Skills Acquisition, and Training Structure

Advances in Medical Education and Practice
Antoni Sierant, Julia Bijok, Michal Pirozynski Center for Endoscopy Simulation, Center of Postgraduate Medical Education, Warsaw, PolandCorrespondence: Antoni Sierant, Center for Endoscopy Simulation, Center of Postgraduate Medical Education, Marymoncka ...
Sierant A, Bijok J, Pirozynski M
doaj

Mapping the colon through the colonoscope’s coordinates – The Copenhagen Colonoscopy Coordinate Database

Scientific Data
Colonoscopy is the leading endoscopic technique when it comes to implementing artificial intelligence-based tools to optimize the procedure. However, no database consisting of the colonoscope’s coordinates exists, allowing for a mapping with timestamps ...
Kristoffer Mazanti Cold +8 more
doaj +1 more source

debriefing
emergency medicine