Results 91 to 100 of about 7,632,569 (355)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

A General Simulation Framework for Supply Chain Modeling: State of the Art and Case Study

, 2010
Nowadays there is a large availability of discrete event simulation software that can be easily used in different domains: from industry to supply chain, from healthcare to business management, from training to complex systems design.
Cimino, Antonio, Longo, Francesco, Mirabelli, Giovanni   +2 more
core   +1 more source

Facilitating the analysis of a UK national blood service supply chain using distributed simulation [PDF]

, 2009
In an attempt to investigate blood unit ordering policies, researchers have created a discrete-event model of the UK National Blood Service (NBS) supply chain in the Southampton area of the UK.
Alder, D., Concannon, K.H., Fujimoto, R.M., Fujimoto, R.M., Gan, B.P., Gan, B.P., Hibino, H., Ieee, Ieee, Ieee, Ieee, Ieee, Kelly Q., Korina Katsaliaki, Kuhl, F., Lendermann, P., Marr D.T., Mertins, K., Mustafee, N., Mustafee, N., Mustafee, N., Navonil Mustafee, Rabe, M., Rabe, M., Revetria, R., Sally Brailsford, Simon J.E. Taylor, Simul8 Corporation., Strassburger, S., Strassburger, S., Straßburger, S., Sun Microsystems Limited., Swain, J.J., Taylor, S.J.E., Taylor, S.J.E., Tewoldeberhan, T.W., US Department of Defense Modeling and Simulation Office., Wang, X.   +37 more
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A Detailed Monte-Carlo Simulation for the Belle TOF System [PDF]

, 2002
We have developed a detailed Monte Carlo simulation program for the Belle TOF system. Based on GEANT simulation, it takes account of all physics processes in the TOF scintillation counters and readout electronics.
B.C.K Casey, Clark, D.W Kim, G Varner, H Kichimi, Hawkes, J Yashima, J Zhang, J.H Kim, J.L Rodriguez, J.W Nam, Kichimi, Kichimi, M Jones, M Peters, N Gabyshev, S.L Olsen, Suda, T.H Kim, Y Zheng, Y.I Choi, Y.J Kwon   +21 more
core   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Promoting leadership and communication skills in emergency medicine residents: the role of High-Fidelity Simulation

Emergency Care Journal
The residency program in Emergency Medicine should include formal training in Non-Technical Skills (NTS). We evaluated the effectiveness of a program based on High-Fidelity Simulation (HFS) to improve the leadership and communication skills of residents
Lorenzo Maiorano, Elisa Capretti, Anna De Paris, Alessio Prota, Elisa Paolucci, Rudy Marchetti, Alessandro Coppa, Caterina Savinelli, Riccardo Pini, Francesca Innocenti   +9 more
doaj   +1 more source

The Complexity of Bisimulation and Simulation on Finite Systems

, 2018
In this paper the computational complexity of the (bi)simulation problem over restricted graph classes is studied. For trees given as pointer structures or terms the (bi)simulation problem is complete for logarithmic space or NC$^1$, respectively.
Ganardi, Moses, Göller, Stefan, Lohrey, Markus   +2 more
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Consent to medical student teaching: an observational, cross-sectional study exploring the patient view

BMC Medical Education
Background New Zealand guidelines stipulate that patient consent is obtained for medical student involvement in clinical care, however, patients’ preferences regarding consent for medical student teaching have not been widely explored.
Niki Newman, Fraser McKenzie, Jonathan M. Wells, Tim Wilkinson, John Dean, Matthew Doogue, Lutz Beckert   +6 more
doaj   +1 more source