Results 51 to 60 of about 1,304,479 (314)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The Repast Simulation/Modelling System for Geospatial Simulation [PDF]

, 2007
The use of simulation/modelling systems can simplify the implementation of agent-based models. Repast is one of the few simulation/modelling software systems that supports the integration of geospatial data especially that of vector-based geometries ...
Crooks, AT
core  

A New Perspective for Urban Development Boundary Delineation Based on the MCR Model and CA-Markov Model

Land, 2022
In order to control the development of urban space, it is important to explore scientific methods to provide a reference for regional territorial space planning. On the basis of the minimum cumulative resistance (MCR) model and the cellular automaton (CA)
Siqi Yi, Yong Zhou, Qing Li
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

An analysis of internal/external event ordering strategies for COTS distributed simulation [PDF]

, 2003
Distributed simulation is a technique that is used to link together several models so that they can work together (or interoperate) as a single model.
Simon J. E. Taylor, Mustafee, N, Navonil Mustafee, Taylor, SJE   +3 more
core  

Addendum to "A generalized Nash equilibrium for a bio-economic problem of fishing" [PDF]

Journal of Applied Research on Industrial Engineering, 2017
In [1] the authors have set up a bio-economic equilibrium model to understand the interactions between three fish populations and seek to maximize the profits of fishermen.
Imane Agmour, Naceur Achtaich, Youssef EL Foutayeni, Mohamed Khaladi, Abdelmounaim Zegzouti   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

4SEE: a model-driven simulation engineering framework for business process analysis in a SaaS paradigm [PDF]

, 2013
The intrinsic geographical distribution and the increasing complexity are two significant properties of modern business processes (BPs) that have not been fully addressed by existing simulation tools for BP analysis.
Gianni, D, Bocciarelli, P, D'AMBROGIO, ANDREA, Gianni, D., D'Ambrogio, A   +4 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

BioSimGrid: grid-enabled biomolecular simulation data storage and analysis [PDF]

, 2006
In computational biomolecular research, large amounts of simulation data are generated to capture the motion of proteins. These massive simulation data can be analysed in a number of ways to reveal the biochemical properties of the proteins. However, the
Tai, KH, Sansom, Mark, Wu, Bing, Jeffreys, Paul, Ng, Muan Hong, Murdock, SE, Tai, Kaihsu, Johnston, Steven, Fangohr, Hans, Cox, SJ, Wu, B, Ng, MH, Fangohr, H, Sansom, Mark S. P., Essex, JW, Essex, Jonathan W., Sansom, Mark S.P., Murdock, Stuart E., Johnston, S, Jeffreys, P, Cox, Simon J.   +20 more
core   +2 more sources