Results 61 to 70 of about 1,304,479 (314)

Measuring Decentrality in Blockchain Based Systems

open access: yesIEEE Access, 2020
Blockchain promises to provide a distributed and decentralized means of trust among untrusted users. However, in recent years, a shift from decentrality to centrality has been observed in the most accepted Blockchain system, i.e., Bitcoin. This shift has
Sarada Prasad Gochhayat   +5 more
doaj   +1 more source

Statistical analysis of parallel simulations [PDF]

open access: yesProceedings of the 18th conference on Winter simulation - WSC '86, 1986
This paper addresses statistical issues that arise when discrete event simulations are run on parallel processing computers. First, the statistical properties of estimates obtained by parallel distributed simulation and parallel independent replications are compared.
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Coastal ecosystems simulation: a decision tree analysis for Bivalve's growth conditions [PDF]

open access: yes, 2012
The usage of data mining models has the main purpose of discovering new patterns from dataset analysis by extracting knowledge from data and converting it to information.
António Pereira   +3 more
core   +1 more source

Simulation Experiments in Practice: Statistical Design and Regression Analysis [PDF]

open access: yes
In practice, simulation analysts often change only one factor at a time, and use graphical analysis of the resulting Input/Output (I/O) data. The goal of this article is to change these traditional, naïve methods of design and analysis, because ...
Kleijnen, J.P.C.
core   +4 more sources

Spatial-Temporal Evolution of Agricultural Carbon Balance at Township Scale and Carbon Compensation Zoning: A Case Study of Guangshui City, Hubei Province

open access: yesLand
Optimizing agricultural carbon compensation zoning is crucial for establishing robust mechanisms in agricultural carbon compensation management, with significant implications for achieving national “dual carbon” strategic objectives. This study employs K-
Zhengkun Yang   +3 more
doaj   +1 more source

Object-Oriented and Deep-Learning-Based High-Resolution Mapping from Large Remote Sensing Imagery

open access: yesCanadian Journal of Remote Sensing, 2021
Land use and land cover (LULC) mapping is a basic research topic in geography. In deep-learning (DL)-based LULC mapping, there are primarily the following issues: training and testing samples for DL are typically annotated by indoor visual interpretation
Yijin Wu   +3 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Simulation-based optimization of agent scheduling in multiskill call centers. [PDF]

open access: yes, 2007
We examine and compare simulation-based algorithms for solvingthe agent scheduling problem in a multiskill call center.This problem consists in minimizing the total costs of agents underconstraints on the expected service level per call type,per period ...
Gendreau, M.   +14 more
core  

Simulation-based impact analysis for sustainable manufacturing design and management [PDF]

open access: yes, 2018
This research focuses on effective decision-making for sustainable manufacturing design and management. The research contributes to the decision-making tools that can enable sustainability analysts to capture the aspects of the economic, environmental ...
Gbededo, Mijoh Ayodele
core   +1 more source

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