Results 121 to 130 of about 672,616 (313)
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
An investigation of constraint-based risk management for collaborative design
, 2011 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In the context of internationally challenging economic, design has been regarded as a key factor in assisting design and manufacturing companies to survive.
Ruan, Jian
core
An aerospace component cost modelling study for value driven design [PDF]
, 2009 Demand is increasing in aero-engine products for better efficiency and environmental performance whilst keeping the cost low. Unlike performance, the physics behind cost is least understood.
Cheung, J. M. W. +5 more
core
The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti +5 more
wiley +1 more source
An agent based compositional framework for supply chain simulation [PDF]
To survive in an ever increasing global and competitive marketplace, organisations are forging strategic alliances to gain a competitive advantage over their rivals.
Arunachalam, Raghu
core
Design and Simulation of Ornithopter based on Four-bar Mechanism
Jixie chuandong, 2017 In order to study the twin joint structure of bird wings,a flapping wing structure based on four-bar mechanism is designed based on the principle of bionics. The brushless motor driving two stage reducer,provides input for four-bar mechanism.
Zhao Zhifang +5 more
doaj
Arthritis Care &Research, EarlyView.Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis +77 more
wiley +1 more source
Physics Based Design, the Future of Modeling and Simulation
Acta Polytechnica, 2005 This paper discusses the expanding role of modeling and simulation in the design and development of electrical power systems. The concepts of physics-based design and building blocks are introduced to show how complex systems may be simplified.
T. S. Ericsen
doaj
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source
Developing a pedagogical model for simulation-based healthcare education
, 2015 The purpose of my research is to facilitate healthcare education in simulation-based learning environments (SBLEs). The specific aim of the present study is to give examples of how simulationbased education can be applied in pedagogically appropriate ...
Keskitalo, Tuulikki +1 more
core