Results 91 to 100 of about 898,870 (314)

Design Interference Detector-A Tool for Predicting Intrinsic Design Failures [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityIntricate failures at the system integration phase of the design are mostly generated by interactions of product modules or/and engineering domains.
D’Amelio, V., Tomiyama, Tetsuo
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Mechanical Structure Design of Wearable Assistive Robot Driven by ADAMS System

open access: yesIEEE Access
Currently wearable assistive robot has been widely researched and applied in many fields. Aiming at the problems of difficult and time-consuming handling of goods, a wearable assistive robot using automatic dynamic analysis of mechanical systems is ...
Xiaona Cai
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Integrated Process Simulation and Die Design in Sheet Metal Forming

open access: yes, 2007
During the recent 10-15 years, Computer Aided Process Planning and Die Design evolved as one of the most important engineering tools in sheet metal forming, particularly in the automotive industry. This emerging role is strongly emphasized by the rapid
Lukács, Zsolt, Tisza, Miklós, Gál, G.
core  

Object-Oriented Simulation Model Generation in an Automated Control Software Development Framework [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityThe automated development of control software for mechatronic systems requires the integration of control models for design and verification purposes.
van Tooren, M. J. L., Foeken, M. J.
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

An aerospace component cost modelling study for value driven design [PDF]

open access: yes, 2009
Demand is increasing in aero-engine products for better efficiency and environmental performance whilst keeping the cost low. Unlike performance, the physics behind cost is least understood.
Cheung, J. M. W.   +5 more
core  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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