Results 121 to 130 of about 729,727 (315)

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Kriging Models That Are Robust With Respect to Simulation Errors

open access: yes
In the field of the Design and Analysis of Computer Experiments (DACE) meta-models are used to approximate time-consuming simulations. These simulations often contain simulation-model errors in the output variables.
Siem, A.Y.D., Hertog, D. den
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Reusable modelling and simulation of flexible manufacturing for next generation semiconductor manufacturing facilities [PDF]

open access: yes, 2003
Automated material handling systems (AMHS) in 300 mm semiconductor manufacturing facilities may need to evolve faster than expected considering the high performance demands on these facilities.
El-Kilany, Khaled S.
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Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi   +9 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Modeling and simulation of reliability function of a homogeneous hot double redundant repairable system

open access: yes, 2020
Calculation of a system reliability function is one of the principal problems in reliability theory. It is well known that even for the simplest double redundant repairable system this function has not been analytically calculated yet in case when ...
Kozyrev D., Rykov V., Zaripova E.
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T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

Bankpro Commercial Bank Simulation

open access: yes, 1992
The commercial bank simulation described here was programmed with the objective of creating a game which would create a realistic banking environment while minimizing the number of periodic decisions made by the student teams. The simulation consists of:
Cretien, Paul D.
core  

Agent-Based Simulation Of Crowd At The Tawaf Area. [PDF]

open access: yes, 2007
Every year during the Hajj season there is a concentration of more than two million people within the vicinity of the Masjid Al-Haram. Congested areas, such as the tawaf,, may reach beyond a safe level of four people per square meter during this peak ...
Haron, F.   +2 more
core  

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