Results 51 to 60 of about 729,727 (315)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
New Fixed-Point Theorems on an S-metric Space via Simulation Functions
Mathematics, 2019 In this paper, we prove new fixed-point theorems using the set of simulation functions on an S-metric space with some illustrative examples. Our results are stronger than some known fixed-point results.
Nabil Mlaiki +2 more
doaj +1 more source
Correlation functions and computer simulations
Nuclear Physics B, 1981 If the equilibrium properties of a statistical system are obtained by solving numerically the associated Langevin equation describing the approach to equilibrium, the connected correlation functions can be computed directly with small effort and high precision.
openaire +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
, 2018 11 páginasThis paper presents a comparison of several well-known dispatching rules hybridised with Monte Carlo simulation to solve the Permutation Flow Shop Scheduling Problem with stochastic processing times.
González Neira, Eliana María +5 more
core +1 more source
, 2020 Aims Predictions of medium to long-term changes in soil organic carbon (SOC) stocks involve simulation models with plant carbon (C) inputs estimated from crop yields using crop harvest indices and allometric scaling involving fixed root-to-shoot ratios ...
Katterer, T. +8 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Fixed point theorems for simulation functions in $\mbox{b}$-metric spaces via the $wt$-distance
Applied General Topology, 2017 The purpose of this article is to prove some fixed point theorems for simulation functions in complete b-metric spaces with partially ordered by using wt-distance which introduced by Hussain et al.
Chirasak Mongkolkeha +2 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Best Proximitiy Point Results for Geraghty Type ?-Proximal Contractions with an Application
Axioms, 2019 In this study, we establish the existence and uniqueness theorems of the best proximity points for Geraghty type ?-proximal contractions defined on a complete metric space.
Hüseyin Işık +3 more
doaj +1 more source