Results 111 to 120 of about 5,438,311 (249)

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi   +9 more
wiley   +1 more source

Hydro–Wind–Photovoltaic Multi-Energy Centralized Control Systems and Digital Twin-Based Simulation Training Platforms: A Review

open access: yesEnergies
With the rapid development of clean energy, hydro–wind–photovoltaic multi-energy systems require centralized control centers with stronger operational support, coordinated dispatch, and emergency response capabilities. However, safety constraints in real
Yan Ren   +5 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

SIMULATION OPTIMIZATION BASED ON A HETEROGENEOUS COMPUTING ENVIRONMENT [PDF]

open access: yes, 2001
We solve a simulation optimization using a deterministic nonlinear solver based on the sample-path concept. The method used a quadratic model built from a collection of surrounding simulation points.
Sinapiromsaran, Krung, Ferris, Michael
core  

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

Process-based simulation library SALMO-OO for lake ecosystems

open access: yes, 2005
Over the past three decades numerous lake ecosystem models incorporating algal population dynamics have been developed and published. However, most of these models have been constructed, calibrated and validated ad hoc to suit one specific lake ...
Recknagel, F., Zhang, H., Cetin, L.
core  

Benchmark functions for simulation.

open access: yes, 2016
Benchmark functions for simulation.
Mousa Shamsi (3079245)   +2 more
core   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

An analysis of internal/external event ordering strategies for COTS distributed simulation [PDF]

open access: yes, 2003
Distributed simulation is a technique that is used to link together several models so that they can work together (or interoperate) as a single model.
Simon J. E. Taylor   +3 more
core   +1 more source

The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti   +5 more
wiley   +1 more source

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