Results 31 to 40 of about 5,438,311 (249)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Nonlinear AnalysisOne of the most significant hypotheses in fixed point theory is the nonexpansivity condition of contractive mappings. This property is crucial as operators that do not satisfy this criterion may lack fixed points.
Antonio Francisco Roldán López de Hierro +1 more
doaj +1 more source
Preference modelling approaches based on cumulative functions using simulation with applications [PDF]
, 2012 In decision making problems under uncertainty, Mean Variance Model (MVM) consistent with Expected Utility Theory (EUT) plays an important role in ranking preferences for various alternative options.
Fatah, Khwazbeen Saida
core
, 2020 Introduction Working under extreme stress can cause medical professionals to deviate from clinical guidelines even if they know of their existence, let alone in situations such as COVID-19 where guidelines are unclear, fluid, and resources limited.
Rim Banat +11 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Simulation as an intuition building tool for factory physics [PDF]
, 2007 In today's manufacturing environment it is absolutely critical to be competitive in order to guarantee a company's sustainability. One way to achieve this sustainability is to count on management's ability to effectively make decisions dealing with its ...
González Gómez, José Arturo +1 more
core +2 more sources
On Suzuki-Proinov Type Contractions in Modular $b$-Metric Spaces with an Application
Communications in Advanced Mathematical SciencesIn this paper, by taking ${{\mathcal C}_\mathcal{A}}-$simulation function and Proinov type function into account, we set up a new contraction mapping called Suzuki$-$Proinov $\mathpzc{Z^*}_{\aE^*}^{\aR}(\alpha)-$contraction, including both rational ...
Abdurrahman Büyükkaya +1 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Graphical simulation of functions
IOP Conference Series: Materials Science and Engineering, 2021 Abstract In scientific research, it is normal practice to arrive at a description of the analyzed process with the function of one independent variable and the participation of several parameters, which are also assumed to be independent quantities, but in the study they have relatively constant values.
G I Shivacheva, K B Yankov
openaire +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source