Results 31 to 40 of about 6,360,945 (304)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Outreach simulation for system improvement: a novel advocacy and reporting process

open access: yesAdvances in Simulation
Introduction Healthcare simulation programmes measuring their value risk wasting resources in attempts to prove they impact patient outcomes. Simulation is one of many strategies used to enhance healthcare systems, and proving specific correlation with ...
A. St-Onge-St-Hilaire   +5 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Distributed Interactive Simulation: Operational Concept Draft 2.2 [PDF]

open access: yes, 1993
Report to present the operational concept for distributed interactive simulation, with the understanding that DIS will evolve over time as more participants in training and testing communities articulate their ...
University of Central Florida Institute for Simulation and Training
core  

Promote Scientific Discourse, Not Lawsuits

open access: yesTelehealth and Medicine Today, 2022
Pacira Biosciences initiated a lawsuit asserting trade libel over articles and related materials produced by Anesthesiology. The defendants filed a motion to dismiss.
Vikram Dhillon, Matthew Fisher
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Proof-of-Concept of the Virtual Reality Comprehensive Balance Assessment and Training for Sensory Organization of Dynamic Postural Control

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Accurate quantification of the impact of visual, somatosensory, and vestibular systems on postural control may inform tailor-made balance intervention strategies.
Sanghee Moon   +6 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Understanding the Role of Achievements in Game-Based Learning

open access: yesInternational Journal of Serious Games, 2016
The objective of the current research was to examine whether one potentially effective gaming strategy—achievements—has a positive impact on learning in a game-based environment. An achievement in a video game is a reward or recognition earned by players
Lucas Blair   +3 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

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