Results 31 to 40 of about 247,099 (269)

SIMULATOR FOR TRAINING MINING LOCOMOTIVE DRIVERS

open access: yesRudarsko-geološko-naftni Zbornik, 2022
Training of mining locomotive drivers using simulators will increase the efficiency and intensity of training. Due to this, a decrease in financial and time expenditures for training a driver, an increase in the safety and productivity of his labour will
Artem S. Аkulov   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Memory Fault Simulator for Static-Linked Faults [PDF]

open access: yes, 2006
Static linked faults are considered an interesting class of memory faults. Their capability of influencing the behavior of other faults causes the hiding of the fault effect and makes test algorithm design and validation a very complex task.
Di Natale, Giorgio   +9 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Simulator Panel Surya Ekonomis untuk Pengujian MPPT pada Kondisi Berbayang Sebagian

open access: yesJurnal Nasional Teknik Elektro dan Teknologi Informasi, 2020
Makalah ini menjelaskan tentang simulator panel surya yang ekonomis tetapi bisa beroperasi dengan kebutuhan pengujian metode Maximum Power Point Tracking (MPPT), khususnya untuk kondisi berbayang sebagian. Simulator terdiri atas power supply DC dan panel
Novie Ayub Windarko   +3 more
doaj   +1 more source

Control Strategy of Hardware-in-the-Loop Simulator EPOS 2.0 for Autonomous Docking Verification

open access: yes, 2011
This paper briefly describes the hybrid simulator system called European Proximity Operation Simulator (EPOS 2.0) and the development of the hardware-in-the-loop (HIL) docking simulation concept.
Krenn, Rainer   +7 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

spatel093/Otoscopy-Simulator-Data: Otoscopy Simulator

open access: yes, 2022
Files for creating an otoscopy simulator and data from ...
spatel093
core   +1 more source

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