Results 41 to 50 of about 315,394 (309)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Improving Coral Grow-Out Through an Integrated Aquaculture Approach
Some coral species in natural reef systems derive benefits from fish which live in close association with them. This study investigates the benefits of incorporating fish in ex situ coral culture to enhance coral physiological performance.
Rachel C. Neil +7 more
doaj +1 more source
Design of cooling system in space solar array simulator
For the high power solar array simulator, the requirements such as high power, miniaturization and modularization are higher. In this paper the total power of the simulator is 2.4 kW with the chassis height is no more than 2U.
Zhang Jian +3 more
doaj +1 more source
The ability to appropriately perceive distances in activities of daily living, such as driving, is necessary when performing complex maneuvers. With aging, certain driving behaviors and cognitive functions change; however, it remains unknown if ...
Luis Eudave +6 more
doaj +1 more source
Boolean notions of correctness are formalized by preorders on systems. Quantitative measures of correctness can be formalized by real-valued distance functions between systems, where the distance between implementation and specification provides a measure of “fit” or “desirability.” We extend the simulation preorder to the quantitative setting, by ...
Cerný +3 more
openaire +3 more sources
Simulation Techniques for Cosmological Simulations [PDF]
42 pages, 16 figures, accepted for publication in Space Science Reviews, special issue "Clusters of galaxies: beyond the thermal view", Editor J.S. Kaastra, Chapter 12; work done by an international team at the International Space Science Institute (ISSI), Bern, organised by J.S. Kaastra, A.M. Bykov, S.
Dolag K. +4 more
openaire +6 more sources
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Efficacy of a Three-Dimensional-Printed Training Simulator for Endoscopic Biopsy in the Stomach
Background/AimsWe used three-dimensional (3D) printing technology to create a new biopsy simulator for the stomach and investigated its efficacy and realism in endoscopic biopsy training.Methods : A novel stomach biopsy simulator, with 10 biopsy sites ...
Sunpyo Lee +10 more
doaj +1 more source

