Results 41 to 50 of about 247,099 (269)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Improving Coral Grow-Out Through an Integrated Aquaculture Approach
Aquaculture NutritionSome coral species in natural reef systems derive benefits from fish which live in close association with them. This study investigates the benefits of incorporating fish in ex situ coral culture to enhance coral physiological performance.
Rachel C. Neil +7 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Design of cooling system in space solar array simulator
Dianzi Jishu Yingyong, 2019 For the high power solar array simulator, the requirements such as high power, miniaturization and modularization are higher. In this paper the total power of the simulator is 2.4 kW with the chassis height is no more than 2U.
Zhang Jian +3 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2022 The ability to appropriately perceive distances in activities of daily living, such as driving, is necessary when performing complex maneuvers. With aging, certain driving behaviors and cognitive functions change; however, it remains unknown if ...
Luis Eudave +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Efficacy of a Three-Dimensional-Printed Training Simulator for Endoscopic Biopsy in the Stomach
Gut and Liver, 2018 Background/AimsWe used three-dimensional (3D) printing technology to create a new biopsy simulator for the stomach and investigated its efficacy and realism in endoscopic biopsy training.Methods : A novel stomach biopsy simulator, with 10 biopsy sites ...
Sunpyo Lee +10 more
doaj +1 more source
Mood and simulator sickness after truck simulator exposure [PDF]
, 2014 Objectives: Studies involving simulators are increasingly popular. We examined to what extent exposure to a variety of test conditions on the simulator affects the level of mood and severity of simulator sickness.
Łukasz Dziuda +3 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Sterols are key to coral larvae survival, swimming capacity, and thermal tolerance
Communications BiologyCorals at very early life stages face high mortality bottlenecks, limiting natural stock-recruitment and the success of restoration and aquaculture strategies reliant on sexual reproduction.
Jennifer L. Matthews +12 more
doaj +1 more source