Results 141 to 150 of about 15,260 (213)
Perception of crossmodal simultaneity is not transitive
, 2007 Machulla T-K, Di Luca M, Ernst MO. Perception of crossmodal simultaneity is not transitive. Perception.
Machulla, T-K +3 more
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USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
SIMULTANEITY WITH DOWNWARD SLOPING DEMAND
This paper considers anew the simultaneity problem that arises when observations of transactions are used to study the demand behavior of price- taking consumers. Simultaneity is shown to be a problem of censored outcomes.
Charles F. Manski
core
PRICE SENSITIVITIES FOR U.S. FROZEN DAIRY PRODUCTS [PDF]
Price elasticities and flexibilities for a system of frozen dessert products are estimated from scanner data. Simultaneity tests reject exogeneity of conditional expenditures, but not prices or quantities, at the weekly level.
Maynard, Leigh J., Narayanan, V. Venkat
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FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Music and simultaneity in Hermann Broch's "Bergroman" Der Versucher
, 1977 References to the various aspects of the symbolical correspondence between simultaneity and music are omnipresent in Hermann Broch's literary and theoretical endeavors. This analysis will investigate their implications in detail.
Stevens, Suzanne
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