Results 81 to 90 of about 15,260 (213)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Aim: To verify the association between insufficient level of physical activity and multiple health risk behaviors (HRB) in adolescents. Methods: This is an epidemiological study with cross-sectional design carried out in 2016 with 3,617 adolescents aged
Lucas Souza Santos +5 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Simultaneity and “increased present” in the European Spanish perfect
This paper deals with the concept of “simultaneity” in relation to the Spanish Present Perfect based on the descriptions made by Rojo (1974) and Rojo & Veiga (1999), and seeks to link it to other similar concepts proposed by other scholars, such as ...
Susana Azpiazu
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
On the conventional character of simultaneity in special relativity [PDF]
To be able to determine the simultaneity of distant events, one has to make use of a convention. Einstein's famous definition of simultaneity, which sets e=1/2 , is a case of such a convention.
Pabjan, Tadeusz
core
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Children of time: the extended synthesis and major metaphors of evolution
It is time for an expansion and enrichment of evolutionary theory. The "back to the future" proposal contained herein is based on three postulates: 1) Neo-Darwinism is too impoverished for this task; 2) its predecessor, Darwinism, contained the necessary
Daniel R. Brooks, Salvatore J. Agosta
doaj
Simultaneity and non-simultaneity taxis in the German language: temporal and aspectual factors (parametric model) [PDF]
This article, using the digital linguistic paradigm, examines the temporal and aspectual factors that determine the expression of the taxis relations of simultaneity and multitemporality in modern German.
Irina V. Arkhipova
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source

