Results 161 to 170 of about 1,594,945 (309)

Simultaneous Cortical Responses to Multiple Written Words. [PDF]

J Cogn Neurosci
Chauhan V, McCook K, Latif M, White A.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Constructing two-sided simultaneous confidence intervals for multinomial proportions for small counts in a large number of cells [PDF]

Confidence intervals for multinomial proportions are often constructed using large-sample methods that rely on expected cell counts of 5 or greater. In situations that give rise to a large number of categories, the cell counts may not be of adequate size
Warren L. May, William D. Johnson
core  

Simultaneous Versus Interval Sleeve Gastrectomy on Patients Requiring Left Ventricular Assist Devices for End-stage Heart Failure: A Retrospective, Single-Center Cohort Study. [PDF]

Obes Surg
Olavarria O, Naqvi S, Crawford L, Felinski M, Shah S, Walker P, Jumean M, Patel M, Salas I, Patel J, Dinh K, Nathan S, Akkanti B, Kar B, Gregoric I, Bajwa K.   +15 more
europepmc   +1 more source

Simultaneous uniformisation

Suppose that \(\Phi\) is an orientation reversing homeomorphism of one Riemann surface \(R\) onto another Riemann surface \(R^*\). If both surfaces are uniformized by Fuchsian groups of the first kind there is a Kleinian group \(\Gamma\) with invariant components \(W\), \(W^*\) of the set of discontinuity so that \(W/\Gamma\) is conformally equivalent ...
openaire   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Economic Burden, Length of Hospital Stay and Complication of Simultaneous versus Staged Bilateral Hip Arthroplasty: A Hospital Prospective Study

ClinicoEconomics and Outcomes Research
Maoye Shen,1 Wenxue Jiang,1 Ping Qian,1 Gaorui Cai,1 Xiaona Wu,1 Jinghua Wang,2 Xianjia Ning,2 Lixia Song1 1Department of Orthopedics, Shenzhen Third People’s Hospital and the Second Hospital Affiliated with the Southern University of Science and ...
Shen M, Jiang W, Qian P, Cai G, Wu X, Wang J, Ning X, Song L   +7 more
doaj  

Green ratio-manipulating spectrophotometric methods for simultaneous determination of empagliflozin and sitagliptin in pharmaceutical formulations. [PDF]

BMC Chem
Mohamad AAA, Almrasy AA, Abdelazim AH, Taha AS.   +3 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source