Results 31 to 40 of about 772,966 (301)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

DAMPAK KEBIJAKAN DAN MAKROEKONOMI TERHADAP EFEKTIVITAS PENERIMAAN PAJAK DI BURSA EFEK INDONESIA

MIX: Jurnal Ilmiah Manajemen, 2018
. The purpose of this research is to analyse the impact of policy and macroeconomic change on tax revenue and its effectiveness in Consumer Goods Industry sector (CGI) and Infrastructure, Utilities and Transport (IUT) sector.
Mursal Harahap, Bonar M Sinaga, Adler H Manurung, Tubagus Nur Ahmad Maulana   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Diplomatic Engagement and Economic Influence: The Interplay of Chinese OFDI and High-Level Visits

East Asian Economic Review
This study investigates the interdependence between Chinese outward foreign direct investment (OFDI) and high-level visits. Using a simultaneous equation model (SEM) and Three-Stage Least Squares (3SLS), we analyze a panel dataset comprising 146 host ...
Youngjun Choi, Jiaen Li
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Prediction of Individual Tree Diameter and Height to Crown Base Using Nonlinear Simultaneous Regression and Airborne LiDAR Data

Remote Sensing, 2020
The forest growth and yield models, which are used as important decision-support tools in forest management, are commonly based on the individual tree characteristics, such as diameter at breast height (DBH), crown ratio, and height to crown base (HCB ...
Zhaohui Yang, Qingwang Liu, Peng Luo, Qiaolin Ye, Guangshuang Duan, Ram P. Sharma, Huiru Zhang, Guangxing Wang, Liyong Fu   +8 more
doaj   +1 more source

Technical note: Evaluation of the simultaneous measurements of mesospheric OH, HO₂, and O₃ under a photochemical equilibrium assumption – a statistical approach [PDF]

Atmospheric Chemistry and Physics, 2018
This Technical Note presents a statistical approach to evaluating simultaneous measurements of several atmospheric components under the assumption of photochemical equilibrium.
M. Y. Kulikov, A. A. Nechaev, M. V. Belikovich, T. S. Ermakova, A. M. Feigin   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Assessing the Economic Sustainability of Price Intervention Policies: Evidence from Thailand’s Cassava Market

Agriculture
Although many countries have reduced the use of agricultural price intervention policies, such measures continue to be applied intermittently by the Thai government.
Pakapon Saiyut, Supaporn Poungchompu, Patcharee Suriya   +2 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source