Results 61 to 70 of about 582,786 (300)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

A nonlinear simultaneous equation model to determine taper curve.

open access: yesSilva Fennica, 1979
In the original set of equations derived by regression analysis, relative-height diameters (endogenous variables) are presented as nonlinear functions of the other relative-height diameters and of the height of the tree (an exogenous variable).
Kilkki, Pekka, Varmola, Martti
doaj   +1 more source

SIMULTANEOUS EQUATIONS BAYESIAN BOOTSTRAP [PDF]

open access: yes
This paper introduces a semi-parametric bootstrapping approach to Bayesian analysis of structural parameters in simultaneous equation systems that extends the single and multivariate regression approaches of Heckelei and Mittelhammer (1996, 2002) to ...
Heckelei, Thomas   +1 more
core   +1 more source

Identification and Estimation in an Incoherent Model of Contagion [PDF]

open access: yes, 2007
This paper deals with the issues of identification and estimation in the canonical model of contagion advanced in Pesaran and Pick (2007). The model is a two-equation nonlinear simultaneous equations system with endogenous dummy variables; it also ...
Massacci, Daniele
core   +5 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Models with Simultaneous Equations for Local Development [PDF]

open access: yesTheoretical and Applied Economics, 2010
This paper presents a model based on simultaneous equations with statistical determined parameters for describing the evolution of important issues relating to local development.
Ani MATEI, Stoica ANGHELESCU
doaj   +1 more source

Dynamic Interaction Between Microfinance and Household Well-Being: Evidence from the Microcredit Progressive Model for Sustainable Development

open access: yesEconometrics
Microfinance aims to promote financial inclusion among underprivileged individuals, particularly through progressive microcredit, which enables borrowers to access increasing loan amounts over time.
Ahmad Alqatan   +5 more
doaj   +1 more source

Pitfall of simple permanent income hypothesis model [PDF]

open access: yes
Permanent Income Hypothesis (hereafter, PIH) is one of the central concepts in macroeconomics. Single equation version of PIH is often appeared in textbooks and academic papers.
Kazuto Masuda
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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