Results 111 to 120 of about 447,032 (297)

The Nonexistence of Instrumental Variables [PDF]

open access: yes
The method of instrumental variables (IV) and the generalized method of moments (GMM) and their applications to the estimation of errors-in-variables and simultaneous equations models in econometrics require data on a sufficient number of instrumental ...
George S. Tavlas   +2 more
core  

Wave dispersion derived from the square-root Klein-Gordon-Poisson system

open access: yes, 2013
Recently there has been great interest around quantum relativistic models for plasmas. In particular striking advances have been obtained by means of the Klein-Gordon-Maxwell system, which provides a first order approach to the relativistic regimes of ...
Haas, Fernando
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Effective Actions for the SU(2) Confinement-Deconfinement Phase Transition

open access: yes, 2005
We compare different Polyakov loop actions yielding effective descriptions of finite-temperature SU(2) Yang-Mills theory on the lattice. The actions are motivated by a simultaneous strong-coupling and character expansion obeying center symmetry and ...
Andreas Wipf   +4 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Asymptotics in Minimum Distance from Independence Estimation [PDF]

open access: yes
In this paper we introduce a family of minimum distance from independence estimators, suggested by Manski's minimum mean square from independence estimator.
Donald J. Brown, Marten H. Wegkamp
core  

Evaluation of a Novel Electric Health Record Sidecar Application to Display Rheumatoid Arthritis Clinical Outcomes During Clinic Visits: Results of a Stepped‐Wedge Cluster Randomized Pragmatic Trial

open access: yesArthritis Care &Research, EarlyView.
Objective We developed a novel electronic health record sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk   +16 more
wiley   +1 more source

Parameter estimation for a computable general equilibrium model: a maximum entropy approach [PDF]

open access: yes
We introduce a maximum entropy approach to parameter estimation for computable general equilibrium (CGE) models. The approach applies information theory to estimating a system of nonlinear simultaneous equations. It has a number of advantages.
Arndt, Channing   +2 more
core  

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie   +3 more
wiley   +1 more source

Fear of floating and fear of pegging: An empirical anaysis of de facto exchange rate regimes in developing countries [PDF]

open access: yes
This paper uses a panel probit model with simultaneous equations to explain the joint determination of de facto and de jure exchange rate regimes in developing countries since 1980.
von Hagen, Jürgen, Zhou, Jizhong
core  

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